Results 251 to 260 of about 411,261 (379)

Anthracyclines attenuate Nrf1-dependent proteolytic pathways and potentiate proteasome inhibitor cytotoxicity. [PDF]

Mol Biol Cell
Vangala JR, Ward MA, Albalawi B, Elshazly AM, Hosseini N, Shen S, Byers HA, Carter C, Liu J, Radhakrishnan SK.   +9 more
europepmc   +1 more source

Granulocyte Macrophage Colony-stimulating Factor Signaling and Proteasome Inhibition Delay Neutrophil Apoptosis by Increasing the Stability of Mcl-1 [PDF]

, 2004
Mathieu Derouet, Luke W. Thomas, Andrew Cross, Robert J. Moots, Steven W. Edwards   +4 more
openalex   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source

Unveiling the Potential of a New β-Cyclodextrin-Suxibuzone Conjugate in Proteasome Regulation. [PDF]

ChemMedChem
Bognanni N, Zimbone S, Giuffrida ML, Di Natale G, Milardi D, Vecchio G, Lanza V.   +6 more
europepmc   +1 more source

Supplementary Data from Proteasome Subunits Differentially Control Myeloma Cell Viability and Proteasome Inhibitor Sensitivity

, 2023
Chang‐Xin Shi, Yuan Xiao Zhu, Laura A. Bruins, Cecília Bonolo de Campos, William Stewart, Esteban Braggio, A. Keith Stewart   +6 more
openalex   +1 more source

REEP1 Accumulation Disrupts ER Integrity and Drives Spinal Motoneuron Degeneration in Distal Hereditary Motor Neuropathy

Advanced Science, EarlyView.
REEP1 contributes to endoplasmic reticulum (ER) shaping. Variants either cause cortical motoneuron degeneration and hereditary spastic paraplegia (HSP) or spinal motoneuron degeneration and distal hereditary motor neuropathy (dHMN). Knockout causes less complex ER structures and cortical motoneuron loss.
Andrea Bock, Mona Schurig, Miles Willoughby, Andrea Mirecki, Eric Seemann, Kateryna Lohachova, Istvan Katona, Sonnhild Mittag, Lutz Liebmann, Patricia Franzka, Mehdi Heidari Horestani, Mukhran Khundadze, Thorsten Mosler, Timothy Louie, Marianne de Visser, Marian A. J. Weterman, Michael Kiehntopf, Christian Beetz, Sandor Nietzsche, Otmar Huber, Joachim Weis, Michael M. Kessels, Ramachandra M. Bhaskara, Britta Qualmann, Ivan Đikić, Christian A. Hübner   +25 more
wiley   +1 more source

Absence of the axon initial segment in sensory neuron enhances resistance to amyotrophic lateral sclerosis. [PDF]

Brain
Tra NT, Kiryu-Seo S, Kida H, Wakatsuki K, Tashiro Y, Tsutsumi M, Ataka M, Iguchi Y, Nemoto T, Takahashi R, Katsuno M, Kiyama H.   +11 more
europepmc   +1 more source

LMP2 expression and proteasome activity in NOD mice [PDF]

, 2000
Benedikt M. Kessler, Ana‐Maria Lennon‐Duménil, Mari L. Shinohara, Myra A. Lipes, Hidde L. Ploegh   +4 more
openalex   +1 more source

Proteasome Structure and Assembly.

Journal of Molecular Biology, 2017
Lauren Budenholzer, C. L. Cheng, Yanjie Li, M. Hochstrasser   +3 more
semanticscholar   +1 more source

Proteogenomic Characterization Reveals Metabolic Vulnerabilities and Aberrant Phosphorylation in Colorectal Metastasis to Liver

Advanced Science, EarlyView.
This study provides a multi‐omics landscape of treatment‐naïve colorectal liver metastasis and reveals dysregulated molecules and cellular pathways. SHMT1 and NDRG1 Ser330 phosphorylation are demonstrated to display crucial roles in tumorigenesis and liver metastasis. Two proteomics subtypes (metabolism and RNA function) with distinct clinical outcomes
Wensi Zhao, Lei Zhao, Yannan Lian, Zhiwei Liu, Yaqi Li, Xuege Wang, Mingya Zhang, Ni Li, Jingli Guo, Danqing Shen, Shaobo Mo, Jiahao Li, Linhui Zhai, Jiahui Ni, Sangkyu Lee, Bin Liu, Jing Li, Fei Wang, Junjie Peng, Jun Qin, Minjia Tan   +20 more
wiley   +1 more source