Results 71 to 80 of about 204,426 (234)

Supplementary Figures 1 - 4 from <i>BRAF</i> V600E Is a Determinant of Sensitivity to Proteasome Inhibitors

open access: gold, 2023
Davide Zecchin   +11 more
openalex   +2 more sources

Proteasome&nbsp;Inhibitors&nbsp;Reduce&nbsp;Thrombospondin-1&nbsp;Release&nbsp;in&nbsp;Human&nbsp;Dysferlin-Deficient&nbsp;Myotubes [PDF]

open access: gold, 2020
Esther Fernández‐Simón   +6 more
openalex   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

Supplement 1. sgRNA sequences targeting PSMC1 to C6 from CRISPR Genome-Wide Screening Identifies Dependence on the Proteasome Subunit PSMC6 for Bortezomib Sensitivity in Multiple Myeloma

open access: gold, 2023
Chang‐Xin Shi   +10 more
openalex   +1 more source

Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance [PDF]

open access: gold, 2021
Imtiyaz Yaseen   +10 more
openalex   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

open access: yesAdvanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang   +9 more
wiley   +1 more source

20S Proteasome [PDF]

open access: hybrid, 2020
National Cancer Institute
openalex   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

open access: yesAdvanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo   +5 more
wiley   +1 more source

Molecular Cardiotoxic Effects of Proteasome Inhibitors Carfilzomib and Ixazomib and Their Combination with Dexamethasone Involve Mitochondrial Dysregulation

open access: green, 2023
Ayşe Tarbın Jannuzzi   +5 more
openalex   +2 more sources

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