Results 61 to 70 of about 98,536 (126)

Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome [PDF]

, 2015
The well described conventional antigen processing pathway is accountable for most peptides that end up in MHC class I molecules at the cell surface. These peptides experienced liberation by the proteasome and transport by the peptide transporter TAP ...
Aldrich, Aldrich, Bartoszewski, Bland, Braud, Cascio, Cerundolo, Chapman, Chemali, Chen, Christianson, Cresswell, Crotzer, Dalbey, de Almeida, de la Salle, Del Val, Durgeau, El Hage, English, Fluhrer, Friedmann, Garstka, Geier, Gil-Torregrosa, Glas, Henderson, Hermann, Hu, Hughes, Jahreiss, Jensen, Jeon, Johnson, Kessler, Kim, Kisselev, Klein, Kloetzel, Koble, Lampen, Lampen, Lampen, Lautscham, Lee, Lemberg, Lemberg, Leonhardt, Levine, Levy, Li, Lilley, Lorente, Lorente, Loureiro, Lu, Lyko, Martoglio, Medina, Mijaljica, Momburg, Munz, Nagarajan, Nam, Nam, Neefjes, Oehler, Oliveira, Oliveira, Oliveira, Oliveira, Parmentier, Rapoport, Reits, Reits, Riebeling, Rock, Rodgers, Sandberg, Saric, Saric, Schrul, Sebzda, Seidah, Seidah, Seidel, Seifert, Serwold, Snyder, Snyder, Snyder, Song, Spee, Susan-Resiga, Targett-Adams, Targett-Adams, Tey, Thomas, Tiwari, Urban, van de Weijer, van der Wal, van Hall, van Hall, Van Hall, Van Kaer, Voss, Vyas, Wang, Wearsch, Wei, Weihofen, Weihofen, Weinzierl, Wiertz, Wolpert, Yamada, Yewdell, Yorimitsu, York, York, Zimmer   +121 more
core   +2 more sources

Purification and characterisation of 20S proteasome from ostrich skeletal muscle and its role in meat tenderisation [PDF]

, 2004
The proteasome is renowned for its high molecular weight, multisubunit and mulicatalytic nature. One of its many suggested roles is the degradation of myofibrillar proteins, and therefore it has been proposed to play a role in the meat tenderisation ...
Thomas, Adele René
core   +1 more source

An in vitro model of murine middle ear epithelium. [PDF]

, 2016
Otitis media (OM) or middle ear inflammation is the most common pediatric disease and leads to significant morbidity. Although understanding of underlying disease mechanisms is hampered by complex pathophysiology it is clear that epithelial abnormalities
Admyre, Amesara, Atherton, Bakaletz, Barnes, Bartlett, Bernstein, Bingle, Butler, Casey, Cash, Choi, Choi, Chun, Clarke, Cody, Davidson, Davies, Gao, Gaschler, Hendrixson, Herman, Horani, Horani, Juhn, Kapsogeorgou, Keller, Kerschner, Kesimer, Kim, Kondo, Lechner, Lim, Lim, Lim, Lim, Liu, Loonen, Matsui, Mcguire, Moon, Moon, Musa, Nakamura, Pillai, Portier, Preciado, Preciado, Roy, Rye, Rye, Schachern, Schousboe, Straetemans, Takeno, Thompson, Toyama, Tsuchiya, Ueyama, Vaishnava, Val, Valadi, Van Blitterswijk, Van Niel, van Rozendaal, Vladar, Woo, Woodfield, Woodworth, Wright, Wu, Yamaya, You, You   +73 more
core   +3 more sources

Controlled sumoylation of the mevalonate pathway enzyme HMGS-1 regulates metabolism during aging [PDF]

, 2014
Many metabolic pathways are critically regulated during development and aging but little is known about the molecular mechanisms underlying this regulation. One key metabolic cascade in eukaryotes is the mevalonate pathway.
Bardenheier, Annabelle, Bening-Abu-Schach, Ulrike, Boxem, Mike, Broday, Limor, Ching, Kaitlin, Chou, Tsui-Fen, Koorman, Thijs, Mishra, Prashant, Podolsky, Lisa, Sapir, Amir, Sternberg, Paul W., Tsur, Assaf   +11 more
core   +3 more sources

Studies of Recombinant TWA1 Reveal Constitutive Dimerization [PDF]

, 2017
The mammalian muskelin/RanBP9/C-terminal to LisH (CTLH) complex and the Saccharomyces cerevisiae glucose-induced degradation (GID) complex are large, multi-protein complexes that each contain a RING E3 ubiquitin ligase.
Adams, Jo, Baker, Genevieve, Francis, Ore, Race, Paul   +3 more
core   +3 more sources

Mechanisms of HIV Protein Degradation into Epitopes: Implications for Vaccine Design [PDF]

, 2014
The degradation of HIV-derived proteins into epitopes displayed by MHC-I or MHC-II are the first events leading to the priming of HIV-specific immune responses and to the recognition of infected cells.
Boucau, Julie, Dinter, Jens, Kourjian, Georgio, Le Gall, Sylvie, Rucevic, Marijana   +4 more
core   +2 more sources

Identification Of Novel Biomarker For Human Uterine Leiomyosarcoma [PDF]

, 2018
Sarcomas are neoplastic malignancies that typically arise in tissues of mesenchymal origin. The identification of novel molecular mechanisms leading to sarcoma formation and the establishment of new therapies has been hampered by several critical factors.
Aburatani, Hiroyuki, Hayashi, Takuma, Horiuchi, Akiko, Ishiko, Osamu, Kanai, Yae, Konishi, Ikuo, Tonegawa, Susumu, Yaegashi, Nobuo, Zharhary, Dorit   +8 more
core   +1 more source

Familial Alzheimer's Disease Mutations in Presenilin Generate Amyloidogenic Ab Peptide Seeds [PDF]

, 2016
Recently it was proposed that the familial Alzheimer’s disease (FAD) causing presenilin (PSEN) mutations PSEN1-L435F and PSEN1-C410Y do not support the generation of Aβ-peptides from the amyloid precursor protein (APP).
Chavez-Gutierrez, L, De Strooper, B, Saido, TC, Saito, T, Veugelen, S   +4 more
core  

Functional characterization of two M42 aminopeptidases erroneously annotated as cellulases [PDF]

, 2012
Several aminopeptidases of the M42 family have been described as tetrahedral-shaped dodecameric (TET) aminopeptidases. A current hypothesis suggests that these enzymes are involved, along with the tricorn peptidase, in degrading peptides produced by the ...
Bauvois, C., Brandt, N., Dutoit, R., Legrain, C.   +3 more
core  

Proteolysis of defensive proteins in peritonitis exudate [PDF]

, 1991
Assfalg-Machleidt, Irmgard, Billing, A., Fröhlich, D., Jochum, Marianne, Machleidt, W.   +4 more
core   +1 more source