Botulinum neurotoxin type A: actions beyond SNAP-25? [PDF]
Botulinum neurotoxin type A (BoNT/A), the most potent toxin known in nature which causes botulism, is a commonly used therapeutic protein. It prevents synaptic vesicle neuroexocytosis by proteolytic cleavage of synaptosomal-associated protein of 25 kDa ...
Lacković, Zdravko, Matak, Ivica
core +1 more source
Clinical activity of carfilzomib correlates with inhibition of multiple proteasome subunits: Application of a novel pharmacodynamic assay [PDF]
et al,, Vij, Ravi
core +2 more sources
Proteolysis of defensive proteins in peritonitis exudate [PDF]
Assfalg-Machleidt, Irmgard+4 more
core +1 more source
Prolyylioligopeptidaasiestäjän vaikutukset α-synukleiiniin perustuvissa Parkinsonin taudin malleissa [PDF]
Parkinson's disease (PD) is characterized by a slow and gradual loss of neurons and subsequent loss of neurotransmitter dopamine in the movement-related nigrostriatal brain tracts.
Savolainen, Mari
core
Meta-analysis of RNA-Seq datasets allows a better understanding of P. tricornutum cellular biology, a requirement to improve the production of Biologics. [PDF]
Boulogne I, Toustou C, Bardor M.
europepmc +1 more source
A kinetic model for USP14 regulated substrate degradation in 26S proteasome. [PDF]
Wu D, Ouyang Q, Wang H, Mao Y.
europepmc +1 more source
Structural Insights into Salinosporamide a Mediated Inhibition of the Human 20S Proteasome. [PDF]
Sülzen H+4 more
europepmc +1 more source
Proteasome Augmentation Mitigates Age-Related Cognitive Decline in Mice. [PDF]
Parker D+4 more
europepmc +1 more source
Glutathione-associated redox regulation alleviates radio-resistance of canine cancer stem-like cells with low proteasome activity. [PDF]
Sung K+8 more
europepmc +1 more source