Results 231 to 240 of about 3,106,146 (396)

Mechanistic insights into proteasome inhibitor MG132 induced apoptosis in melanoma A375 cells. [PDF]

Sci Rep
Xu M, Zhang Z, He X, Zhang P, Zhang H, Xia Y, Zhou J, Liu J, Ye X, Liu J.   +9 more
europepmc   +1 more source

In-class transition (iCT) of proteasome inhibitor-based therapy: a community approach to multiple myeloma management. [PDF]

Blood Cancer J, 2023
Rifkin RM, Girnius SK, Noga SJ, Birhiray RE, Kambhampati S, Manda S, Lyons RM, Yimer HA, Cherepanov D, Lloyd E, Whidden P, Richter J.   +11 more
europepmc   +1 more source

Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system.

Current Cancer Drug Targets, 2014
Q. Dou, J. Zonder
semanticscholar   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

Phase 1 study of weekly dosing with the investigational oral proteasome inhibitor ixazomib in relapsed/refractory multiple myeloma.

Blood, 2014
Shaji K. Kumar, W. Bensinger, T. Zimmerman, C. Reeder, J. Berenson, D. Berg, A. Hui, N. Gupta, A. Di Bacco, Jiang Yu, Y. Shou, R. Niesvizky   +11 more
semanticscholar   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Proteasome inhibitor MG132 reverses multidrug resistance of gastric cancer through enhancing apoptosis and inhibiting P-gp [PDF]

, 2008
Yafei Zhang, Yongquan Shi, Xiaohua Li, Rui Du, Guanhong Luo, Lin Xia, Wenqi Du, Bei Chen, Huihong Zhai, Kaichun Wu, Daiming Fan   +10 more
openalex   +1 more source

Venetoclax-proteasome inhibitor-dexamethasone for unfit patients with blastic plasmacytoid dendritic cell neoplasm. [PDF]

Blood Adv
Khalife-Hachem S, Pages A, Akoury E, Bonnet S, Birsen R, Busquet C, Contejean A, Danu A, de Botton S, de Charette M, Dumas PY, Jaccard A, Marfaing-Koka A, Willekens C, Deconinck E, Ghez D.   +15 more
europepmc   +1 more source

Ancistrocladinium A Induces Apoptosis in Proteasome Inhibitor-Resistant Multiple Myeloma Cells: A Promising Therapeutic Agent Candidate. [PDF]

Pharmaceuticals (Basel), 2023
Brünnert D, Seupel R, Goyal P, Bach M, Schraud H, Kirner S, Köster E, Feineis D, Bargou RC, Schlosser A, Bringmann G, Chatterjee M.   +11 more
europepmc   +1 more source

Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease

Clinical Cancer Research, 2014
Antonio Garcia-Gomez, Dalia Quwaider, M. Canavese, E. Ocio, Z. Tian, J. Blanco, A. Berger, C. Ortíz-de-Solórzano, Teresa Hernández-Iglesias, A. Martens, R. Groen, Joaquín Mateo-Urdiales, Susana Fraile, Miguel Galarraga, D. Chauhan, J. S. San Miguel, N. Raje, M. Garayoa   +17 more
semanticscholar   +1 more source