Results 91 to 100 of about 1,742,110 (296)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Protected areas, wildlife conservation and local welfare [PDF]
The establishment and expansion of protected areas in Africa have been motivated by the aspiration of increased wildlife abundance. During the past decades, however, this practise has been subject to a massive debate.
Anne Borge Johannesen
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Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Frontiers in Plant Science, 2016 The aim of the study was to monitor the effects of exogenous melatonin on cucumber (Cucumis sativus L.) chloroplasts and explore the mechanisms through which it mitigates chilling stress. Under chilling stress, chloroplast structure was seriously damaged
Hailiang Zhao +22 more
doaj +1 more source
Sicilian Protected Areas Among Tourist Exploitation and Environmental Guardianship [PDF]
This report pursues the objective to define the connection that ties exploitation of the environment quality in the protected areas and the opportunities of economic and tourist development.
Vito Genna
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The Pitcairn Islands The world's Largest Fully Protected Marine Reserve [PDF]
, 2015 In March 2015, the United Kingdom declared the world's largest fully protected marine reserve in the remote waters surrounding the Pitcairn Islands in the South Pacific Ocean. The designation marks the first time any government has combined creation of a
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Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Analysis of protected areas of nature on the global level and a comparison to Europe and Slovenia [PDF]
, 2014 Protected areas are an important instrument in the successful\ud long-term preservation of biodiversity; however, despite the\ud continued growth in their number and size, they still cannot\ud prevent biodiversity loss.
Bevc Šekoranja, Bernarda +1 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
A simple Preservation Method of Bird Feces for DNA Analysis: A Case Study on Chicken and Quail
Tikrit Journal for Agricultural SciencesStandardized methods for fecal sample collection and safe long-distance transportation for DNA extraction are yet to be identified. We compared four different preservation methods for bird fecal samples: storage in 75% and 100% ethanol, freezing at −20 ...
Ahmed Khalid +4 more
doaj +1 more source