Results 91 to 100 of about 1,753,274 (299)

L´impact des aires protégées et des utilisations anthropogènes du sol sur la regeneration des terrains boisés à Acacia dans l´est du Burkina Faso [PDF]

open access: yes, 2008
Regeneration success, persistence strategies (seedlings vs. coppicing), and population trend of Acacia spp. were tested under two land-use regimes in eastern Burkina Faso: (i) protected areas shielded to livestock grazing pressure, to logging, and using ...
Guinko, Sita   +4 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Marine Protected Areas: Smart Investments in Ocean Health [PDF]

open access: yes, 2015
Expanding ocean protection could return an increase in jobs, resources and services that far outweigh the costs, according to an analysis of new research commissioned by WWF on marine protected areas.
Emilie Reuchlin-Hugenholtz   +1 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Commercialization of Holidays in the Protected Natural Areas - Form of the Sustainable Development in Tourism [PDF]

open access: yes
Sustainable development of tourism in the protected areas should be regarded as a continuous improvement process in the management quality of the protected natural areas that are included in the tourist circuit as well as of the ecological tourism ...
Andreea Băltăreţu   +4 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Melatonin increases the chilling tolerance of chloroplast in cucumber seedlings by regulating photosynthetic electron flux and the ascorbate-glutathione cycle

open access: yesFrontiers in Plant Science, 2016
The aim of the study was to monitor the effects of exogenous melatonin on cucumber (Cucumis sativus L.) chloroplasts and explore the mechanisms through which it mitigates chilling stress. Under chilling stress, chloroplast structure was seriously damaged
Hailiang Zhao   +22 more
doaj   +1 more source

Untangling the Benefits of Protected Areas in Fisheries [PDF]

open access: yes
Studies of marine protected areas as a tool for fisheries management have shown that protected areas have the potential to improve the level of resource rent generated in the fishery.
Greenville, Jared W.   +1 more
core   +1 more source

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