Results 61 to 70 of about 7,937,209 (346)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Emerging Microbes and Infections, 2020 The H7N9 influenza virus has been circulating in China for more than six years. The neuraminidase (NA) has gained great concern for the development of antiviral drugs, therapeutic antibodies, and new vaccines.
Fei-Fei Xiong +6 more
doaj +1 more source
Epilepsia, 2005 Summary: Brain injury evolves over time, often taking days or even weeks to fully develop. It is a dynamic process that involves immediate oxidative stress and excitotoxicity followed by inflammation and preprogrammed cell death. This article presents a brief overview of mechanisms of neuroprotection in the developing brain.
openaire +2 more sources
Agents, Coercive Learning, and Social Protection Policy Diffusion in Africa [PDF]
, 2021 Stephen Devereux, Anna Wolkenhauer
openalex +1 more source
Overlay Protection Against Link Failures Using Network Coding [PDF]
, 2010 This paper introduces a network coding-based protection scheme against single and multiple link failures. The proposed strategy ensures that in a connection, each node receives two copies of the same data unit: one copy on the working circuit, and a ...
Kamal, Ahmed +5 more
core +5 more sources
Electroshock protection circuit [PDF]
, 1973 Circuit was developed to prevent accidental shock through electrodes used to test subjects as part of Skylab program. This circuit is placed between electrical apparatus and electrode that is attached to patient's body.
Heskett, H., Inglis, A. L., Meincer, J.
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Power, politics and privilege: public health at the Thai-Burma border
Forced Migration Review, 2016 Participants in a field-research methods course on refugee health at the Thai-Burma border learned that beyond the biological vectors and disease processes that contribute to human suffering, power, politics and privilege play central roles in negatively
Nikhil A Patel +3 more
doaj
Water soluble polysaccharides from Spirulina platensis exhibited cyto/DNA protection and suppress the growth of gastric cancer cells via modulation of galectin-3 [PDF]
, 2021 Vinayak Uppin +2 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source