Results 91 to 100 of about 2,508,909 (311)

Analysing the environmental harms caused by coal mining and its protection measures in permafrost regions of Qinghai–Tibet Plateau

open access: yesEnvironmental Protection and Natural Resources, 2017
The coal mining has brought a series of ecological problems and environmental problems in permafrost regions. Taking Muli coal-mining area as an example, this article attempts to analyse the environmental harms caused by coal mining and its protection ...
Wei Cao   +3 more
doaj   +1 more source

Certain Considerations Regarding the Attributions of the Romanian Guardianship Court in the Protection of the Minors

open access: yesJournal of Legal Studies, 2020
The minors’ vulnerability led to the adoption of certain special means of protection. Among them, special protection measures and adoption play a special role.
Creț Daniela Cristina
doaj   +1 more source

Working Report #3: Use of Legal Measures and Formal Authority (Service Provider Perspectives) [PDF]

open access: yes, 2009
The focus of this report is, across service delivery models, how front-line protection workers viewed their formal authority role and the extent to which they relied on legal measures in order to achieve protection goals.
Cameron, Gary, Hazineh, Lirondel
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Problems of training specialists in the field of information security

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The problem of training specialists in the field of information security seems relevant given the lack of specialists capable of countering new threats. Objectively, there is a significant shortage of qualified specialists who could be trained
I. I. Livshits
doaj   +1 more source

Botryosphaeria dieback of grapevine

open access: yesGlasnik Zaštite Bilja, 2022
Grapevine is one of the most important culture grown in the world. It is attacked by a large number of phytopathogenic fungi, of which species of the family Botryosphaeriaceae pose one of the most significant threats.
Elena Petrović   +2 more
doaj  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Ensuring information security in the production network of an industrial enterprise

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The purpose of this article is to explore issues and develop approaches to enhance information security in the production control networks of industrial enterprises to the necessary level.
A. R. Aydynan, D. G. Kirsanov
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

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