Results 71 to 80 of about 560,325 (264)
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
TSUNAMIS AND THEIR IMPACT ON HUMAN ACTIVITIES [PDF]
The regions where most of tsunamis originate are Japan, Peru, Chile, the New Guinea and the Solomon Islands. The emergence of tsunamis may be caused by the following factors: 1) earthquakes; 2) volcanic eruptions; 3) rockfalls; 4) landslides; 5 ...
Sergey GOVORUSHKO
doaj
Protective measurement and the PBR theorem
To appear in Protective Measurement: Towards a New Understanding of Quantum Mechanics, ed.
Hetzroni, Guy, Rohrlich, Daniel
openaire +2 more sources
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
In this article I make a reflection about the art. 1 L0 1/2004 of 28 December of integral Protection Measures against Gender Violence (law 1/2004) and its relations with sexual trafficking victims, who are absent in these regulation, and as a result any ...
Izaskun Orbegozo
doaj
THE IMPACT OF VOLCANIC ERUPTIONS ON HUMAN ACTIVITY [PDF]
Altogether about 2500 volcanoes exist on Earth, and during the last 3500 years, 959 of them erupted. About 360 mln. people live in dangerous proximity to actve volcanoes. On average about 50 volcanoes erupt each year.
Sergey GOVORUSHKO
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source

