Results 61 to 70 of about 2,531,538 (311)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The meaning of protective measurements [PDF]
Foundations of Physics, 1996 Protective measurements, which we have introduced recently, allow to measure properties of the state of a single quantum system and even the Schr dinger wave itself. These measurements require a protection, sometimes due to an additional procedure and sometimes due to the potential of the system itself.
Aharonov, Yakir +2 more
openaire +2 more sources
Fast semiautomatic dimensional test set and data logger [PDF]
, 1975 System measures and records tolerance deviations of thermal-protection ceramic tiles in less than 30 seconds.
Meunier, G. E.
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 2020 In order to minimise the health hazard to the welder by hazardous substances at the workplace, technical, organisational and—in certain situations—also personal protective measures shall be implemented according to the applicable regulations. The efficiency of the implemented protective measures shall be checked by verification of their efficiency.
Vilia Elena Spiegel-Ciobanu +2 more
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Personal protective measures [PDF]
, 2018 With the financial support of Internal Security Fund Police Programme European Commission Directorate General Home Affairs. This project has been founded with support from the European Commission. This publication reflects the views only of the authors, and European Commission cannot be held responsible for any use which may be made of the information ...
Michalski, Aleksander +4 more
openaire +3 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Las medidas de protección del informante: la base de la funcionalidad del sistema
Revista Vasca de Administración PúblicaThe construction of an effective whistleblower protection system requires the establishment of a prior legal framework that generates trust and legal certainty for whistleblowers.
Javier Eduardo Quesada Lumbreras
doaj +1 more source