Results 51 to 60 of about 660,420 (310)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Renmin Zhujiang, 2021 The wetland in the Liaohe River Nature Reserve has played a crucial role in pollutant purification and biodiversity protection for the Liaohe River Basin.This paper reviews the evolution of the wetland ecosystem of the Liaohe River Nature Reserve over ...
SUN Xiangru, CHEN Jiabo, WANG Yanjie
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Protecting the neighborhood: Extreme measures [PDF]
Proceedings of the National Academy of Sciences, 1998 In the unending wars of organism vs. organism, the growth of bacteriophage and the defenses raised by bacteria were among the first recognized and continue to provide new variations and insights on ways to defend oneself. A paper in this issue of the Proceedings demonstrates that prokaryotes, like eukaryotes, have chosen proteolytic self-destruction as
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An Overview of Legal Instruments and Other Measures to Aid in the Protection and Valuation of Indigenous Knowledge [PDF]
, 2019 This paper outlines the legal instruments and other measures used to support the protection of Indigenous Knowledge (IK), with a view to attributing market value to IK.
Bodle, Kerry +3 more
core +1 more source
TSUNAMIS AND THEIR IMPACT ON HUMAN ACTIVITIES [PDF]
Analele Universității din Craiova. Seria Geografie, 2009 The regions where most of tsunamis originate are Japan, Peru, Chile, the New Guinea and the Solomon Islands. The emergence of tsunamis may be caused by the following factors: 1) earthquakes; 2) volcanic eruptions; 3) rockfalls; 4) landslides; 5 ...
Sergey GOVORUSHKO
doaj
Інтродукція Рослин, 2014 The biological and ecological characteristics of some ornamental willows collection of M.M. Gryshko National Botanical Garden of the NAS of Ukraine are given. The composition of pests, their biology and protection measures are described.
O.P. Gromova, O.M. Gorelov
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
THE IMPACT OF VOLCANIC ERUPTIONS ON HUMAN ACTIVITY [PDF]
Analele Universității din Craiova. Seria Geografie, 2007 Altogether about 2500 volcanoes exist on Earth, and during the last 3500 years, 959 of them erupted. About 360 mln. people live in dangerous proximity to actve volcanoes. On average about 50 volcanoes erupt each year.
Sergey GOVORUSHKO
doaj