Results 61 to 70 of about 2,508,909 (311)
Wakefield Land Conservation Education & Outreach Project [PDF]
The Town of Wakefield has experienced an unprecedented growth explosion in the past seven years. Pressures to use heretofore undeveloped land for the construction of residential housing has threatened the natural resources of this community.
Barstow, Cindy, Schlenker, Cheri
core +2 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
TSUNAMIS AND THEIR IMPACT ON HUMAN ACTIVITIES [PDF]
The regions where most of tsunamis originate are Japan, Peru, Chile, the New Guinea and the Solomon Islands. The emergence of tsunamis may be caused by the following factors: 1) earthquakes; 2) volcanic eruptions; 3) rockfalls; 4) landslides; 5 ...
Sergey GOVORUSHKO
doaj
UK’s Implementation of the Anti-Circumvention Provisions of the EU Copyright Directive: An Analysis [PDF]
The debate surrounding utilization of technological protection measures to secure copyrighted works in the digital arena has raised many an eyebrow in the past few years.
Shah, Aashit
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
THE IMPACT OF VOLCANIC ERUPTIONS ON HUMAN ACTIVITY [PDF]
Altogether about 2500 volcanoes exist on Earth, and during the last 3500 years, 959 of them erupted. About 360 mln. people live in dangerous proximity to actve volcanoes. On average about 50 volcanoes erupt each year.
Sergey GOVORUSHKO
doaj
Spatially explicit groundwater vulnerability assessment to support the implementation of the Water Framework Directive – a practical approach with stakeholders [PDF]
The main objective of the study presented in this paper was to develop an evaluation scheme which is suitable for spatially explicit groundwater vulnerability assessment according to the Water Framework Directive (WFD).
Berkhoff, Karin
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The meaning of protective measurements [PDF]
Protective measurements, which we have introduced recently, allow to measure properties of the state of a single quantum system and even the Schr dinger wave itself. These measurements require a protection, sometimes due to an additional procedure and sometimes due to the potential of the system itself.
Aharonov, Yakir +2 more
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

