Results 71 to 80 of about 163,116 (296)

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

A Criminal Commodity Consensus: The Coloniality of State Power, State Crime and the Transformation of Property Relations in Mexico

State Crime, 2018
Mexican human rights organizations accuse the Mexican military and federal police of having taken part in tens of thousands of forced disappearances in the last decade.
Alke Jenss
doaj   +1 more source

The Amalgam of Rule and Justice: Striking Harmonizations on the Protection of Traditional Knowledge of Indigenous People on The Emerge of Intellectual Property Regime in Indonesia

, 2022
The ratification of Law No. 7 year 1994 concerning The Establishment of WTO following TRIPS agreement raising awareness on the protection of intellectual property rights internationally. Traditional knowledge of indigenous people is a wealth of the nation that has to be protected, but in recent development and existence, it is weak in terms of ...
openaire   +2 more sources

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Do stronger intellectual property rights increase international technology transfer? Empirical evidence from U.S. firm-level panel data [PDF]

One of the alleged benefits of the recent global movement to strengthen intellectual property rights (IPRs) is that such reforms accelerate transfers of technology between countries. The paper examines how technology transfer among U.S.
Fisman, Raymond, Foley, C. Fritz, Branstetter, Lee G.   +2 more
core  

The Effect of Protection Statuses on Protection-Use Balance: The Case of Zelve Open Air Museum (Nevşehir/Avanos)

Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2016
Cappadocia, which is one of Turkey’s most important destinations by virtue of its natural, historical and cultural features, houses unique places within it.
Şenay GÜNGÖR
doaj   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

Extending the concept of property to support the legal protection of digital resources / Wong Wai Wai [PDF]

, 2016
The rapid advancement of information technology and World Wide Web has created many valuable and useful digital resources. As many of these digital resources are commonly, freely available over the internet, people pay little attention for its protection.
Wong, Wai Wai
core  

PREVENT ENVIRONMENTAL DAMAGE DURING ARMED CONFLICT

BRICS Law Journal, 2018
International humanitarian law consists of different rules that are used for protecting people and restricting the methods of warfare. The application of international humanitarian law is not only limited to the protection of victims related to armed ...
Z. M. Jaffal, W. F. Mahameed
doaj   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source