Results 31 to 40 of about 127,204 (261)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Human rotavirus in lambs: infection and passive protection [PDF]
Infection and Immunity, 1977 A human stool filtrate containing rotavirus which was administered orally to gnotobiotic lambs caused diarrhea, virus excretion, development of antibodies to rotavirus, and pathological changes in the villi of the small intestine. Thus, lambs may serve as experimental animals for the study of human rotavirus infections.
D R, Snodgrass +3 more
openaire +2 more sources
Modeling of the corium jet penetration into the pool of volatile coolant under reactor vessel [PDF]
Ядерна фізика та енергетика, 2010 Developed mathematical model and some results of its application to the element of the passive protection system against severe accidents at NPP with water pool under reactor vessel for corium melt and particles’ cooling are presented.
V. H. Moghaddam, I. V. Kazachkov
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Broadly Neutralizing Antibodies for HIV-1 Prevention
Frontiers in Immunology, 2021 Given the absence of an effective vaccine for protection against HIV-1 infection, passive immunization strategies that utilize potent broadly neutralizing antibodies (bnAbs) to block acquisition of HIV-1 are being rigorously pursued in the clinical ...
Stephen R. Walsh, Michael S. Seaman
doaj +1 more source
Thermal Properties of Intumescent Passive Fire Protection Materials
Chemical Engineering Transactions, 2010 preview not available - see full-text PDF article.
G. Berge, K. Opstad
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Archives of Metallurgy and Materials, 2015 The potentiodynamic polarization test and slow strain rate tensile tests of X80 pipeline steel were performed in 0.5M Na2CO3-1M NaHCO3 solution to study the electrochemical and stress corrosion cracking properties.
Zhao W., Zou Y., Xia D.X., Zou Z.D.
doaj +1 more source