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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Broadly Neutralizing Antibodies for HIV-1 Prevention
Given the absence of an effective vaccine for protection against HIV-1 infection, passive immunization strategies that utilize potent broadly neutralizing antibodies (bnAbs) to block acquisition of HIV-1 are being rigorously pursued in the clinical ...
Stephen R. Walsh, Michael S. Seaman
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Modeling of the corium jet penetration into the pool of volatile coolant under reactor vessel [PDF]
Developed mathematical model and some results of its application to the element of the passive protection system against severe accidents at NPP with water pool under reactor vessel for corium melt and particles’ cooling are presented.
V. H. Moghaddam, I. V. Kazachkov
doaj
Lipoarabinomannan in Active and Passive Protection Against Tuberculosis
Glycolipids of the cell wall of Mycobacterium tuberculosis (Mtb) are important immunomodulators in tuberculosis. In particular, lipoarabinomannan (LAM) has a profound effect on the innate immune response. LAM and its structural variants can be recognized
Margarida Correia-Neves +6 more
doaj +1 more source
Protection strategies for next generation passive optical networks -2 [PDF]
Next Generation Passive Optical Networks-2 (NGPON2) are being considered to upgrade the current PON technology to meet the ever increasing bandwidth requirements of the end users while optimizing the network operators' investment. Reliability performance
Chen, J +6 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Thermal Properties of Intumescent Passive Fire Protection Materials
preview not available - see full-text PDF article.
G. Berge, K. Opstad
doaj +1 more source
Application of Fiber Ring for Protection of Passive Optical Infrastructure [PDF]
Today, passive optical networks (PONs) are mostly used as modern high-speed access networks for various applications. However, there are also several specific applications, such as in business, office, army or science sector, which require a complex ...
Lafata, P., Vodrazka, J.
core +1 more source
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source

