Results 41 to 50 of about 127,204 (261)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Passive Protection of Unarmoured Objects

open access: yesJournal of Physics: Conference Series, 2021
Abstract This article presents problems related to passive composite protection of unarmoured objects (helicopters, vehicles, etc.). It is focused on building and testing the different add-on armours (panels) protecting unarmoured objects against small-arms armour piercing projectiles (kinetic energy - KE). It has been illustrated how to
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Passive and active protection against disorders of the gut [PDF]

open access: yesVeterinary Quarterly, 1998
The large surface area of mucosal surfaces, particularly of the gastrointestinal tract, is protected against microorganisms and environmental antigens by various innate factors (e.g., mucins, lactoferrin, and others) and specific antibodies which are of IgA, or in some species, IgG Isotypes.
J, Mestecky, M W, Russell
openaire   +2 more sources

Modeling of spreading of the melted corium jet inside the pool of emergency heat removal during severe accidents at NPP [PDF]

open access: yesЯдерна фізика та енергетика, 2012
Important nuclear power safety problem in touch with modeling of melted corium jet spreading inside the coolant pool is considered in the paper. It appears by development of the passive protection systems against se-vere accidents.
I. V. Kazachkov, O. V. Konoval
doaj  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Problem of corium melt coolability in passive protection systems against severe accidents in the containment [PDF]

open access: yesЯдерна фізика та енергетика, 2018
Paper is devoted to the development of the mathematical model and analysis of the problem of corium melt interaction with low-temperature melting blocks in the passive protection systems against severe accidents at the NPP, which is of high importance ...
Ali Kalvand, I. V. Kazachkov
doaj  

Determinants of Cancer Early Detection Behaviors:Application of Protection Motivation Theory [PDF]

open access: yesHealth Promotion Perspectives, 2015
Background: Cancer is account for 13% of all deaths around the world and is the third cause of mortality in Iran. More than one third of these cases are pre-ventable and about 33% are curable with early detection.
Zohreh Rahaei   +3 more
doaj   +1 more source

Corrosion resistant coating with passive protection and self-healing property based on Fe3O4-MBT nanoparticles

open access: yesCorrosion Communications, 2022
This work synthesized novel Fe3O4 nanoparticles loaded with 2-mercaptobenzothiazole corrosion inhibitors (Fe3O4-MBT NPs), which possessed not only photothermal conversion property but also corrosion inhibition ability.
Jinke Wang   +6 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Home - About - Disclaimer - Privacy