Results 41 to 50 of about 637,639 (284)
As part of the development of a new organic entity, we synthesized a new series of Schiff bases belonging to the imidazo[1,2-a]pyridine (IMP) family, named: (E)-2-methoxy-4-(((2-phenylimidazo[1,2-a]pyridin-3-yl)imino)methyl)phenol(IM1) and (E)-4-(((2 ...
Walid Daoudi +9 more
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Wear analysis of the composite coating in a long sliding time by dissipated energy approach
A wear test of Ti2Ni/TiNi-based coating reinforced by TiC/TiB against a YG6X [94 wt.% tungsten carbide (WC) and 6 wt.% cobalt (Co)] ball in a sliding time of 712 h was carried out using a ball-on-disc reciprocating motion mode.
Shao Jin Zhong +5 more
doaj +1 more source
Research on the protection range of pressure-relief in the mining of upper protective layer
At present, the research on the protective layer pressure relief range mainly focuses on the analysis of the evolution characteristics of coal seam stress, deformation and plastic failure and the pressure relief range of the lower protective layer mining.
QIN Ruxiang1,2, YANG Ke2, CHENG Jian3
doaj +1 more source
The development of high field magnets utilizing Bi-2212 wind & react insert coils
Wind & react Bi-2212 inserts have been manufactured and tested inside a wide-bore NbTi-Nb3Sn magnet providing a background field up to 20T at 4.2K.
Domptail, Fred +9 more
core +1 more source
Corrosion Resistance of Steel/Zinc with Silicate Nanoparticles/Polyurethane Paint Systems in NaCl Solution [PDF]
Surface characteristics and corrosion behaviour of bare electrogalvanized steel coated with polymer/nano-silicate particles added to the electrogalvanizing bath were studied by scanning electron microscopy (SEM), energy dispersive spectrometer (EDXS) and
Di Sarli, Alejandro Ramón +2 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Protective layer mining, as a dominating method for preventing coal and gas outburst, is generally adopted in highly gassy coal mines. In the absence of a suitable thickness coal seam to serve as the protective layer, the rock-coal composite protective ...
Jianhong Ma, Chao Hou, Jiangtao Hou
doaj +1 more source

