Results 91 to 100 of about 467,085 (263)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
GUARDIANSHIP - PROTECTIVE MEASURE
Social Sciences and Education Research ReviewThe way in which personal protection measures are regulated by civil law reflects in all legal systems the degree of concern of the state power to provide the necessary legal framework so that persons who are vulnerable for various reasons can take part in the civil circuit without being prejudiced.
openaire +2 more sources
ON SAFE PLANT AND FODDER PRODUCTION ON 137CS CONTAMINATED SOILS
Радиационная гигиена, 2017 The paper predicts the permissible levels of 137Cs contamination of agricultural lands where the obtaining of farm products in compliance with the existing standards is possible at different countermeasure scales in the affected areas. Exemplified by the
A. V. Panov +4 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Personal protective measures and settings on the risk of SARS-COV-2 community transmission: a case-control study. [PDF]
Front Public Health, 2023 Huguet-Torres A +5 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Effectiveness of Protective Measures and Rules in Reducing the Incidence of Injuries in Combat Sports: A Scoping Review. [PDF]
J Funct Morphol Kinesiol, 2023 Štyriak R +4 more
europepmc +1 more source
Psicologia: Reflexão e Crítica, 2009 Foster care of children and adolescents who have had their rights violated is being discussed both in the scientific literature and in agencies involved in the development of public policies.
Nina Rosa do Amaral Costa +1 more
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