Results 91 to 100 of about 1,245,002 (304)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Survey of Hand Issues Encountered by Hairdressers and Hairdresser Related Professionals: From Epidemiological Data to Clinical Observational Survey Results

open access: yesClinical, Cosmetic and Investigational Dermatology, 2023
Sophie Seité, Guénaëlle Le Dantec, Ann’Laure Demessant-Flavigny, Delphine Kerob Medical Department, La Roche-Posay International, Levallois-Perret, FranceCorrespondence: Delphine Kerob, Cosmétique Active International, La Roche-Posay International, 62 ...
Seité S   +3 more
doaj  

Counterterrorism - Does It Work? [PDF]

open access: yes
The terrorist threat has increased in importance over the last decade and Western governments have implemented a multitude of measures to address it. Their numbers and the significant financial cost they involve have, however, not been matched with an ...
Daniela Pisoiu, Eric van Um
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Goals and Plans in Protective Decision Making [PDF]

open access: yes
Protective decisions are often puzzling. Among other anomalies, people insure against non-catastrophic events, underinsure against catastrophic risks, and allow extraneous factors to influence insurance purchases and other protective decisions.
David H. Krantz, Howard Kunreuther
core  

CUSMA & Technical Protection Measures

open access: yes, 2019
Presented at the 2019 ABC Copyright Conference in Saskatoon, SK.
openaire   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Anthropometry and body composition of 18 year old men according to duration of breast feeding: birth cohort study from Brazil [PDF]

open access: yes, 2003
Objective: To assess the association between duration of breast feeding and measures of adiposity in adolescence. Design: Population based birth cohort study.
Cole, T.J., Treleaven, P., Wells, J.C.K.
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Integration of soil and water conservation measures in an intensively cultivated watershed – a case study of Jihlava river basin (Czech Republic)

open access: yesEuropean Countryside, 2017
Snížení vstupů dusíku a fosforu do povrchových vod z plošných zemědělských zdrojů vyžaduje cílené uplatňování diferencovaných opatření. V rámci studie zaměřené na ochranu půdy a vody v povodí Jihlavy nad vodním dílem Dalešice byly identifikovány oblasti ...
Konečná Jana   +6 more
doaj   +1 more source

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