Results 141 to 150 of about 467,085 (263)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Service Workers' Experience and Perceptions of Workplace Protective Measures During the Onset of COVID-19. [PDF]

Workplace Health Saf, 2023
Rosemberg MS, Adams M, Polick C, Ratliff H, Li WV, Jun J.   +5 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Finite Element Analysis of Protective Measures against Lateral Hinge Fractures in High-Tibial Osteotomy. [PDF]

Adv Orthop
Özmen E, Baris A, Circi E, Yuksel S, Beytemür O.   +4 more
europepmc   +1 more source

Knowledge and Practice of Personal Protective Measures Against COVID-19 in Africa: Systematic Review.

JMIR Public Health Surveill, 2023
Kawuki J, Chan PS, Fang Y, Chen S, Mo PKH, Wang Z.   +5 more
europepmc   +1 more source

Adherence to COVID-19 Protective Measures in a Longitudinal Sample of Male Youth. [PDF]

Int J Behav Med, 2023
Teferra AA, Alalwan MA, Keller-Hamilton B, Roberts ME, Lu B, Paskett ED, Chrzan K, Curran H, Ferketich AK.   +8 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Understanding determinants related to farmers' protective measures towards pesticide exposure: A systematic review. [PDF]

PLoS One
Kangavari M, Sarvi M, Afshari M, Maleki S.   +3 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Author Correction: Welding-induced corrosion and protective measures for clad rebars in neutral chloride environments. [PDF]

Sci Rep
Zhuang Z, Lu W, Zeng L, Tan J, Qian X, Li Z, Jiang W, Xiang Y.   +7 more
europepmc   +1 more source