Results 121 to 130 of about 1,245,002 (304)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Secure remote access to computing sources of the faculty of security system [PDF]

, 2017
In the process of work was created a structure of secure remote access to computing sources of the faculty of security system, a list of information security threats, a list of protective measures, expert evaluation of risks has been done. As a result of
Ковтун, А. С., Малахов, Н. В.   +1 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Conocimiento sobre bioseguridad y aplicación de medidas de protección de las enfermeras del Departamento de Neonatología Hospital Belén de Trujillo 2013 [PDF]

, 2014
El presente estudio descriptivo correlacional, se realizó con el propósito de determinar la relación entre el conocimiento sobre bioseguridad y la aplicación de medidas de protección de las enfermeras del Departamento de Neonatología Hospital Belén de ...
Rodríguez Malaver, Lucy Clarissa, Rodríguez Malaver, Lucy Clarissa, Saldaña Honorio, Teresa Yolanda   +2 more
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

ON SAFE PLANT AND FODDER PRODUCTION ON 137CS CONTAMINATED SOILS

Радиационная гигиена, 2017
The paper predicts the permissible levels of 137Cs contamination of agricultural lands where the obtaining of farm products in compliance with the existing standards is possible at different countermeasure scales in the affected areas. Exemplified by the
A. V. Panov, A. A. Muzalevskaya, R. M. Alexakhin, P. V. Prudnikov, E. V. Vlasenko   +4 more
doaj  

Occupational and Non-Occupational Lead Exposure in Iraq: Clinical Findings and Protective Measures

The Indonesian Journal of Occupational Safety and Health
Introduction: Lead exposure is an important occupational and environmental health problem, especially in the industrial environment. This study determined blood lead levels, associated clinical manifestations and protective measures among petrol refinery
Luay Mohammed, Manoochehr Karami, Yadollah Mehrabi, Seyed Hashemi Nazari   +3 more
doaj   +1 more source

On the Optimal Design of Disaster Insurance in a Federation [PDF]

Recent experience with disasters and terrorist attacks in the US indicates that state and local governments rely on the federal sector for support after disasters occur.
Andrew Haughwout, Timothy J. Goodspeed
core  

GUARDIANSHIP - PROTECTIVE MEASURE

Social Sciences and Education Research Review
The way in which personal protection measures are regulated by civil law reflects in all legal systems the degree of concern of the state power to provide the necessary legal framework so that persons who are vulnerable for various reasons can take part in the civil circuit without being prejudiced.
openaire   +2 more sources