Results 141 to 150 of about 3,289,477 (306)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The impact of protective measures against COVID-19 on the wellbeing of residents in nursing homes and their relatives: a rapid review. [PDF]

BMC Geriatr, 2023
Schneider P, Abt M, Cohen C, Marmier N, Ortoleva Bucher C.   +4 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Awareness of Tehran residents of seven warning signs of cancer, and application of protective measures against cancer

Basic & Clinical Cancer Research, 2013
The present study aimed to determine awareness of Tehran residents of seven warning signs of cancer, and application of protective measures against cancer. 2500 residents of Tehran were selected through systematic cluster random sampling. Data collection
Mitra Zolfaghari, Zohreh Parsa-yekta, Fatemeh Behramnezhad, Anooshirvan Kazemnejad, Zahra Monjamed   +4 more
doaj  

Effect of Protective Measures Adopted in the COVID-19 Pandemic on Hemodialysis Patients. [PDF]

Cureus, 2023
Ferreira DA, Vida C, Mendonça É, Vieira P, Freitas S, Silva G.   +5 more
europepmc   +1 more source

Competitive Environments and Protective Behaviour [PDF]

The class of two-person competition games is introduced and analyzed.For any game in this class the set of Nash equilibria is convex, equilibrium strategies are exchangeable, and all Nash equilibria lead to the same payoff vector.
Borm, P.E.M., Estevez Fernandez, M.A., Fiestras-Janeiro, G.   +2 more
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

DEVELOPMENT OF ADDRESS REHABILITATION STRATEGY FOR THE RURAL TERRITORIES AFFECTED BY THE CHERNOBYL ACCIDENT

Радиационная гигиена, 2016
A methodological approach for the justification of rational countermeasure options in agricultural production in the long term after the Chernobyl NPP accident is presented.
A. V. Panov
doaj  

Resurgence of yellow fever in Africa in 2022: a glance on protective measures. [PDF]

Int J Surg, 2023
Chopra H, Patel N, Sethi Y, Emran TB.
europepmc   +1 more source