RNA‐related functions of BRCA2 in transcription, replication, and genome stability
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Reducing the vulnerability of a platform, i.e., the risk of being affected by hostile objects, is of paramount importance in the design process of vehicles, especially aircraft.
Salvatore Annunziata +3 more
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Competitive Environments and Protective Behaviour [PDF]
The class of two-person competition games is introduced and analyzed.For any game in this class the set of Nash equilibria is convex, equilibrium strategies are exchangeable, and all Nash equilibria lead to the same payoff vector.
Borm, P.E.M. +2 more
core
Lake-Sunapee-Protective-Association/LMP: LSPA LMP database 1986-2023
<p><em>Code and Data Description:</em></p> <p>The code contained in this release documents the quality control measures that have been made to collate the data from the Lake Sunapee Protective Association’s (LSPA) Long-
Weathers, Kathleen +2 more
core +1 more source
Biomimetic multi-layered protective materials with prestress and a periodic laminated structure
The nacreous layer of shells has become an excellent biomimetic template of materials due to its unique structure. Inspired by the highly complex multilayered structure of shells, biomimetic layered composite protective materials with outstanding ...
Xin Liu +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Considerations for selecting protective clothing used in healthcare for protection against microorganisms in blood and body fluids [PDF]
Healthcare workers can be exposed to biological fluids that are capable of transmitting diseases. Those diseases, which are caused by a variety of microorganisms such as, Hepatitis B virus (HBV), Hepatitis C virus (HCV), Ebola Virus, and Human ...
core
ANALYSIS OF THE EFFECTIVENESS OF TACTICAL PROTECTION SCHEMES OF STUDENT HANDBALL TEAMS
. This article discusses approaches to the problem of building team defense tactics. The statistical data of the results of the games of the student handball team were analyzed and structured, as a result of which the effectiveness of tactical defense ...
Aleksandr Vladimirovich Radchenko +1 more
doaj

