Results 221 to 230 of about 3,273,753 (252)

DCMF-PPI: a protein-protein interaction predictor based on dynamic condition and multi-feature fusion. [PDF]

BMC Bioinformatics
Chen S, Zheng A, Yu W, Zhan C.
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Bacterial two-hybrid systems evolved: innovations for protein-protein interaction research. [PDF]

J Bacteriol
Richardson RM, Pascal SM.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Protein-protein interaction prediction using bidirectional GRUs with explicit ensemble. [PDF]

PLoS One
Lan Q, Zheng Z, Tang Z, Qiu X, Yin Z.
europepmc   +1 more source

Integrating Protein-protein Interaction Networks and Machine Learning to Identify Biomarkers of Cancer Onset

Chen H, Ma M, Liu H, Yang Q, Wang J, Zheng J.   +5 more
europepmc   +1 more source

Identification of regulatory sequences in Aca11 and Aca13 for detection of anti-CRISPR and protein-protein interaction. [PDF]

Nucleic Acids Res
Song G, Li J, Han J, Gao X, Tian C, Zhang F, Tian Y.   +6 more
europepmc   +1 more source

Topology-driven negative sampling enhances generalizability in protein-protein interaction prediction. [PDF]

Bioinformatics
Chatterjee A, Ravandi B, Haddadi P, Philip NH, Abdelmessih M, Mowrey WR, Ricchiuto P, Liang Y, Ding W, Mobarec JC, Eliassi-Rad T.   +10 more
europepmc   +1 more source

The signed two-space proximity model for learning representations in protein-protein interaction networks. [PDF]

Bioinformatics
Nakis N, Kosma C, Brativnyk A, Chatzianastasis M, Evdaimon I, Vazirgiannis M.   +5 more
europepmc   +1 more source

MPIDNN-GPPI: multi-protein language model with an improved deep neural network for generalized protein‒protein interaction prediction. [PDF]

BMC Genomics
Li Y, Wang C, Gu H, Long Z, Fan M, Li L.
europepmc   +1 more source