Results 231 to 240 of about 9,193,993 (329)

Identifying subtype-specific molecular pathways in Crohn's disease through RNA-seq and protein-protein interaction network analysis. [PDF]

J Transl Autoimmun
Kolukula SI.
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

EDG-PPIS: an equivariant and dual-scale graph network for protein-protein interaction site prediction. [PDF]

BMC Genomics
Zhang Z, Li Z, Li W, Zhang Q, Xiao J, Ding S, Han Y.   +6 more
europepmc   +1 more source

FAC-PIN: An efficient and fast agglomerative clustering algorithm for protein interaction networks to predict protein complexes and functional modules

, 2013
Mohammad Shamsur Rahman
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Recent Advances and Application of Machine Learning for Protein-Protein Interaction Prediction in Rice: Challenges and Future Perspectives. [PDF]

Proteomes
Merumba SB, Ahmed HO, Fu D, Yang P.
europepmc   +1 more source

Structural Prediction of Protein–Protein Interactions by Docking: Application to Biomedical Problems

, 2017
Didier Barradas‐Bautista, Mireia Rosell, Chiara Pallara, Juan Fernández‐Recio   +3 more
openalex   +2 more sources

Spatially Segregated SNARE Protein Interactions in Living Fungal Cells [PDF]

, 2007
Mari Valkonen, Eric R. Kalkman, Markku Saloheimo, Merja Penttilä, Nick D. Read, R. R. Duncan   +5 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

PPI-ID: Streamlining protein-protein interaction prediction through domain and SLiM mapping. [PDF]

PLoS Comput Biol
Goodwin HV, Atkinson NS.
europepmc   +1 more source