Results 61 to 70 of about 7,140 (156)

Macrophage Extracellular Traps in Immunity and Cancer

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li   +5 more
wiley   +1 more source

Genetic diversity of Streptococcus suis isolates as determined by comparative genome hybridization

open access: yes, 2011
Background Streptococcus suis is a zoonotic pathogen that causes infections in young piglets. S. suis is a heterogeneous species. Thirty-three different capsular serotypes have been described, that differ in virulence between as well as within serotypes.
Smith, H.E.   +42 more
core   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

open access: yesFood Bioengineering, Volume 5, Issue 2, Page 220-243, June 2026.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang   +7 more
wiley   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

open access: yesJournal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo   +9 more
wiley   +1 more source

Affinity maturation shapes the function of agonistic antibodies to peptidylarginine deiminase type 4 in rheumatoid arthritis

open access: yes, 2017
ObjectivesThe citrullinating enzyme peptidylarginine deiminase type 4 (PAD4) is the target of a polyclonal group of autoantibodies in patients with rheumatoid arthritis (RA).
Erika Darrah   +8 more
core   +1 more source

The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma   +6 more
wiley   +1 more source

Genome-Wide Proteomics and Quantitative Analyses on Halophilic Archaea [PDF]

open access: yes, 2008
The aerobic, haloalkaliphilic archaeon Natronomonas pharaonis is able to survive in salt-saturated lakes of pH 11. With genome-wide shotgun proteomics, 886 soluble proteins (929 proteins in total) of the theoretical Natronomonas pharaonis soluble ...
Konstantinidis, Konstantinos   +1 more
core  

Vitamin D Inhibits Expression of Protein Arginine Deiminase 2 and 4 in Experimental Autoimmune Encephalomoyelitis Model Of Multiple Sclerosis

open access: yes, 2014
Indiana University-Purdue University Indianapolis (IUPUI)Multiple sclerosis (MS) is a disabling disease that afflicts an estimated two million people worldwide.
McCain, Travis William
core   +1 more source

Directed evolution of arginine deiminase (ADI) for anti-tumor application

open access: yes, 2010
Arginine deiminase (ADI), an arginine-degrading enzyme, is involved in the first step of arginine dihydrolase pathway. It catalyzes the hydrolysis of L-arginine to form citrulline and ammonia.
Zhu, Leilei
core   +1 more source

Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics

open access: yesMedComm, Volume 7, Issue 6, June 2026.
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou   +10 more
wiley   +1 more source

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