Results 61 to 70 of about 7,140 (156)
Macrophage Extracellular Traps in Immunity and Cancer
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li +5 more
wiley +1 more source
Genetic diversity of
Background Streptococcus suis is a zoonotic pathogen that causes infections in young piglets. S. suis is a heterogeneous species. Thirty-three different capsular serotypes have been described, that differ in virulence between as well as within serotypes.
Smith, H.E. +42 more
core +1 more source
Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang +7 more
wiley +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source
ObjectivesThe citrullinating enzyme peptidylarginine deiminase type 4 (PAD4) is the target of a polyclonal group of autoantibodies in patients with rheumatoid arthritis (RA).
Erika Darrah +8 more
core +1 more source
The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Genome-Wide Proteomics and Quantitative Analyses on Halophilic Archaea [PDF]
The aerobic, haloalkaliphilic archaeon Natronomonas pharaonis is able to survive in salt-saturated lakes of pH 11. With genome-wide shotgun proteomics, 886 soluble proteins (929 proteins in total) of the theoretical Natronomonas pharaonis soluble ...
Konstantinidis, Konstantinos +1 more
core
Indiana University-Purdue University Indianapolis (IUPUI)Multiple sclerosis (MS) is a disabling disease that afflicts an estimated two million people worldwide.
McCain, Travis William
core +1 more source
Directed evolution of arginine deiminase (ADI) for anti-tumor application
Arginine deiminase (ADI), an arginine-degrading enzyme, is involved in the first step of arginine dihydrolase pathway. It catalyzes the hydrolysis of L-arginine to form citrulline and ammonia.
Zhu, Leilei
core +1 more source
Acute Lung Injury: From Molecular Circuits to System‐Level Therapeutics
This visual summary illustrates the paradigm shift from linear pathways to network medicine in ALI. Three interconnected circuits—innate immunity, immunometabolism, and cell death (PANoptosis)—drive disease progression under multiorgan crosstalk (gut–lung, brain–lung).
Yaoli Hou +10 more
wiley +1 more source

