Results 171 to 180 of about 2,229,273 (315)
Corrigendum: HPLC for at-line reaction monitoring and purification improves yield and purity of tRNA
Frontiers in Molecular BiosciencesPolona Megušar +7 more
doaj +1 more source
Optimized Quantitative Bacterial Two-Hybrid (qB2H) for Protein-Protein Interaction Assessment. [PDF]
Comput Struct Biotechnol JGuyot A +8 more
europepmc +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Review and Experimental Analysis of Supervised Learning Systems and Methods for Protein-Protein Interaction Detection. [PDF]
Int J Mol SciTaha K.
europepmc +1 more source
Protein-Protein Interaction Prediction with Identification of Putative Interaction Patterns
, 2007 蛋白質交互用作與其作用位置是了解生物體內運作的重要資訊，現在雖然已發展了許多實驗的方法來加以探測，但能得到的結果仍只是自然界的極小部分，為了增加探索速度，不少研究人員開發計算性的方法來預測，交互作用預測的準確度大致上都可以接受，但不是每個方法都能辨識出交互作用發生的位置，而一般用來預測作用介面的方法大都需要有三級結構的資訊來輔助，可是相較於已經解出的基因體序列，已知的結構資訊實在是太少了，所以這類的方法並不見得適用。 我們提出一個資料探勘演算法，其修改自挖掘關聯規則的Apriori演算法 ...
Tsai, Meng-Jia, 蔡孟家
core
Citation: 'protein–protein interaction' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09878 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
The protein-protein interaction network analysis in idiopathic posterior uveitis. [PDF]
Indian J OphthalmolShariati MM, Moravvej Z.
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source