Results 261 to 270 of about 2,237,588 (315)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Assessment of Anticancer Effect of Rhodium Nanoparticle-based Photodynamic Therapy via Protein-Protein Interaction Network Analysis. [PDF]

J Lasers Med Sci
Hossein-Khannazer N, Arjmand B, Razzaghi Z, Razi F, Bandarian F, Ahmadzadeh A.   +5 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

An efficient framework for protein-protein interaction prediction by integrating stacked denoising autoencoders and random ferns. [PDF]

iScience
Wang Z, Wang L, Li Y, You ZH, Li YC.
europepmc   +1 more source

Evaluating network-based algorithms for protein function prediction using plant protein-protein interaction networks. [PDF]

BMC Plant Biol
Piyatissa MASU, Weeraman JWJK, Sridaran A, De Silva MRP, Tirimanne TLS, Fernando PC.   +5 more
europepmc   +1 more source

Proximity labeling techniques for protein-protein interaction mapping in plants. [PDF]

J Biol Chem
Özmen B, Blaschek L, Ogden M, San Segundo M, Persson S, Zheng S.   +5 more
europepmc   +1 more source

Sequence-Based Protein-Protein Interaction Prediction and Its Applications in Drug Discovery. [PDF]

Cells
Charih F, Green JR, Biggar KK.
europepmc   +1 more source

Disruption of protein-protein interaction hotspots in the C-terminal domain of MLH1 confers mismatch repair deficiency. [PDF]

NAR Cancer
Fishwick KM, Gomez Vieito D, Greco G, Collotta G, Gatti M, Kulik AA, Guérois R, Corbeski I, Phadte AS, Senoussi I, Cejka P, Pluciennik A, Porro A, Sartori AA.   +13 more
europepmc   +1 more source

Predicting interaction-specific protein–protein interaction perturbations by missense variants with MutPred-PPI

Stewart R, Laval F, Coppin G, Spirohn-Fitzgerald K, Tixhon M, Hao T, Calderwood MA, Mort M, Cooper DN, Vidal M, Radivojac P.   +10 more
europepmc   +1 more source

Integrating Protein-protein Interaction Networks and Machine Learning to Identify Biomarkers of Cancer Onset

Chen H, Ma M, Liu H, Yang Q, Wang J, Zheng J.   +5 more
europepmc   +1 more source