Results 261 to 270 of about 2,229,273 (315)

Comprehensive review and assessment of machine learning approaches for host-pathogen protein-protein interaction prediction. [PDF]

Brief Bioinform
Noor F, Tahir Ul Qamar M.
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Exploring How Workflow Variations in Denaturation-Based Assays Impact Global Protein-Protein Interaction Predictions. [PDF]

Mol Cell Proteomics
Reed TJ, Haubold LM, Hutton JE, Troyanskaya OG, Cristea IM.   +4 more
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Integrating Protein-protein Interaction Networks and Machine Learning to Identify Biomarkers of Cancer Onset

Chen H, Ma M, Liu H, Yang Q, Wang J, Zheng J.   +5 more
europepmc   +1 more source

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Protein–protein interactions

Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P., Sutcliffe, Michael J.   +1 more
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DISCOVERING PROTEIN–PROTEIN INTERACTIONS

Journal of Bioinformatics and Computational Biology, 2004
The ongoing genomics and proteomics efforts have helped identify many new genes and proteins in living organisms. However, simply knowing the existence of genes and proteins does not tell us much about the biological processes in which they participate. Many major biological processes are controlled by protein interaction networks.
See-Kiong Ng, Soon-Heng Tan
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Protein-Protein Interactions in Membranes

Protein & Peptide Letters, 2011
In this article we review the current status of our understanding of membrane mediated interactions from theory and experiment. Phenomenological mean field and molecular models will be discussed and compared to recent experimental results from dynamical neutron scattering and atomic force microscopy.
Armstrong, C.L., Sandqvist, E., Rheinstädter, M.C.   +2 more
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Prediction of Protein‐Protein Interactions

Current Protocols in Bioinformatics, 2017
AbstractThe authors provide an overview of physical protein‐protein interaction prediction, covering the main strategies for predicting interactions, approaches for assessing predictions, and online resources for accessing predictions. This unit focuses on the main advancements in each of these areas over the last decade. The methods and resources that
Max, Kotlyar, Andrea E M, Rossos, Igor, Jurisica   +2 more
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Databases for Protein–Protein Interactions

2021
Protein-protein interaction networks have a crucial role in biological processes. Proteins perform multiple functions in forming physical and functional interactions in cellular systems. Information concerning an enormous number of protein interactions in a wide range of species has accumulated and has been integrated into various resources for ...
Natsu, Nakajima, Tatsuya, Akutsu, Ryuichiro, Nakato   +2 more
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Osmolytes and Protein–Protein Interactions

Journal of the American Chemical Society, 2018
Cells survive fluctuations in osmolality by accumulating and depleting highly soluble, usually neutral, small organic compounds. Natural selection has converged on a small set of such molecules, called osmolytes. The biophysical characterization of osmolytes, with respect to proteins, has centered on tertiary structure stability.
Amy E. Rydeen, Eric M. Brustad, Gary J. Pielak   +2 more
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Measuring protein—protein interactions

Current Opinion in Structural Biology, 1998
The binding of one protein to another provokes a variety of biophysical changes that can then be used as a measure of the binding reaction. Optical spectroscopy, particularly fluorescence, is the most flexible technique, but surface plasmon resonance biosensors, microcalorimetry and mass spectroscopy have recently shown significant development.
J H, Lakey, E M, Raggett
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