Results 111 to 120 of about 1,962,138 (310)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Copper-dependent protein-protein interactions studied by yeast two-hybrid analysis
, 2004 An important step in copper homeostasis is delivery of copper to a specific P-type ATPase in the Golgi apparatus (Ccc2 in yeast, ATP7A and ATP7B in humans) by a small copper chaperone protein (Atx1 in yeast, ATOX1 in humans).
Dongen, van, E.M.W.M.; id_orcid +3 more
core +1 more source
Protein–Protein Interactions in Virus–Host Systems
Frontiers in Microbiology, 2017 To study virus–host protein interactions, knowledge about viral and host protein architectures and repertoires, their particular evolutionary mechanisms, and information on relevant sources of biological data is essential.
Anderson F. Brito, John W. Pinney
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Analysis of High-Throughput Data - Protein-Protein Interactions, Protein Complexes and RNA Half-life
, 2009 The development of high-throughput techniques has lead to a paradigm change in biology from the small-scale analysis of individual genes and proteins to a genome-scale analysis of biological systems.
Friedel, Caroline Christina
core
Computational Design and Experimental Characterization of Protein Oligomers [PDF]
, 2004 Previous efforts in designing protein binding interfaces have focused on altering binding specificities. These methods fall short, however, when applied to the design of novel binding sites due to difficulties in accurately modeling protein backbones ...
Huang, Po-Ssu
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
International Journal of Nanomedicine, 2019 Ting Zhang,1,2 Meng Tang,1,2 Ying Yao,1 Ying Ma,1 Yuepu Pu1,2 1Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, Department of Occupational and Environmental Health, School of Public Health & Collaborative Innovation ...
Zhang T, Tang M, Yao Y, Ma Y, Pu Y
doaj
Frontiers in AllergyThe fungus Rhizomucor pusillus CBS 143028 is the source of a novel food called Fermotein®, a whole fungal biomass rich in proteins, fibres, and micronutrients.
Serge A. Versteeg +8 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source