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How to study protein-protein interactions
Physical and functional interactions between molecules in living systems are central to all biological processes. Identification of protein complexes therefore is becoming increasingly important to gain a molecular understanding of cells and organisms ...
Marjetka Podobnik +7 more
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Polyketide Trimming Shapes Dihydroxynaphthalene‐Melanin and Anthraquinone Pigments
Pigments such as anthraquinones (AQs) and melanins are antioxidants, protectants, or virulence factors. AQs from the entomopathogenic bacterium Photorhabdus laumondii are produced by a modular type II polyketide synthase system.
Maximilian Schmalhofer +4 more
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Background Protein-protein interactions are crucial for normal biological processes and to regulate cellular reactions that affect gene expression and function.
Srinivasan Jayashree +3 more
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Molecular basis for azetidine-2-carboxylic acid biosynthesis
Azetidine-2-carboxylic acid (AZE) is a long-known plant metabolite. Recently, AZE synthases have been identified in bacterial natural product pathways involving non-ribosomal peptide synthetases.
Tim J. Klaubert +8 more
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Oligomeric protein structure networks: insights into protein-protein interactions
Background Protein-protein association is essential for a variety of cellular processes and hence a large number of investigations are being carried out to understand the principles of protein-protein interactions.
Brinda KV, Vishveshwara Saraswathi
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Ting Zhang,1,2 Meng Tang,1,2 Ying Yao,1 Ying Ma,1 Yuepu Pu1,2 1Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, Department of Occupational and Environmental Health, School of Public Health & Collaborative Innovation ...
Zhang T, Tang M, Yao Y, Ma Y, Pu Y
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Protein–Protein Interactions in Virus–Host Systems
To study virus–host protein interactions, knowledge about viral and host protein architectures and repertoires, their particular evolutionary mechanisms, and information on relevant sources of biological data is essential.
Anderson F. Brito, John W. Pinney
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The fungus Rhizomucor pusillus CBS 143028 is the source of a novel food called Fermotein®, a whole fungal biomass rich in proteins, fibres, and micronutrients.
Serge A. Versteeg +8 more
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Kaposi’s sarcoma-associated herpesvirus (KSHV) DNA polymerase processivity factor, ORF59, is a lytic protein essential for viral DNA synthesis as part of the core replication complex.
Shannon Harger Payen +4 more
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