Results 161 to 170 of about 184,784 (335)

Exploiting the Unique Properties of Lanthanide Complexes as FRET Probes: from Quantitation to Protein Dynamics

open access: yesAnalysis &Sensing, Volume 3, Issue 1, January 2023., 2023
Lanthanide complexes are ideal donors for FRET (Förster resonance energy transfer) assays with a variety of applications from easy‐to‐use quantitation of proteins to sophisticated experiments giving real‐time information on the movement of proteins. This Review article introduces the principles of using such assays before surveying the full scope of ...
Simon Wheeler, Stephen J. Butler
wiley   +1 more source

Physical and functional interactions between SH2 and SH3 domains of the Src family protein tyrosine kinase p59fyn. [PDF]

open access: green, 1994
Govind Panchamoorthy   +9 more
openalex   +1 more source

Targeting COPA to Enhance Erdafitinib Sensitivity in FGFR‐Altered Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Coatomer protein complex subunit α facilitates the transport of the cargo protein LRPPRC across the Golgi complex and enhances its stability, thereby increasing LRPPRC expression; LRPPRC promotes the stability of ID3 mRNA in an m6A‐dependent manner, thereby decreasing the transcriptional activity of p16 and p21, which leads to increased erdafitinib ...
Huayuan Zhao   +10 more
wiley   +1 more source

Massage‐Mimicking Nanosheets Mechanically Reorganize Inter‐organelle Contacts to Restore Mitochondrial Functions in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li   +12 more
wiley   +1 more source

Properties of FDA-approved small molecule protein kinase inhibitors: A 2024 update

open access: yesPharmacological Research
Owing to the dysregulation of protein kinase activity in many diseases including cancer, this enzyme family has become one of the most important drug targets in the 21st century.
Robert Roskoski, Jr.
doaj  

Comparative analysis of protein kinases and associated domains between Ascomycota and Basidiomycota

open access: yesJournal of Integrative Agriculture, 2019
Protein kinases play an important role in every aspect of cellular life. In this study, we systemically identified protein kinases from the predicted proteomes of 59 representative fungi from Ascomycota and Basidiomycota.
Guo-liang PEI   +3 more
doaj  

Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. [PDF]

open access: yesCell Signal, 2018
Zhang J   +7 more
europepmc   +1 more source

Substrate specificities of tyrosine-specific protein kinases toward cytoskeletal proteins in vitro.

open access: hybrid, 1986
Tetsu Akiyama   +8 more
openalex   +1 more source

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