Results 281 to 290 of about 817,279 (353)

Kinase-Targeted Therapies for Glioblastoma. [PDF]

Int J Mol Sci
Salbini M, Formato A, Mongiardi MP, Levi A, Falchetti ML.   +4 more
europepmc   +1 more source

Mechanism of activation of an ancestral Tec kinase by PIP₃

Krötenheerdt E, von Raußendorf F, Reinhardt R, Piëch L, Wedige N, Nyvall HG, Burke JE, Leonard TA.   +7 more
europepmc   +1 more source

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Protein-tyrosine kinases.

Annual Review of Biochemistry, 1985
Come with us to read a new book that is coming recently. Yeah, this is a new coming book that many people really want to read will you be one of them? Of course, you should be. It will not make you feel so hard to enjoy your life.
T. Hunter, J. Cooper
semanticscholar   +4 more sources

Protein-Tyrosine Kinases

, 2018
R. Geahlen, M. Harrison
semanticscholar   +2 more sources

Conformationally Induced Off-On Cell Membrane Chemosensor Targeting Receptor Protein-Tyrosine Kinases for in Vivo and in Vitro Fluorescence Imaging of Cancers.

Journal of the American Chemical Society, 2018
Molecules capable of monitoring receptor protein-tyrosine kinase expression could potentially serve as useful tools for cancer diagnosis due to the overexpression of tyrosine kinases during tumor growth and metastasis.
Yang Jiao, Jiqiu Yin, Haiyang He, Xiaojun Peng, Qianmiao Gao, Chunying Duan   +5 more
semanticscholar   +1 more source

Protein tyrosine kinases and cancer

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1997
4. Tyrosine kinase activation by mutation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F222 4.1. BCR–ABL and human leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F222 4.2. TEL–ABL and human leukemia . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . F224 4.3.
Brian J. Druker, Kathryn S. Kolibaba
openaire   +2 more sources

Inhibitors of protein tyrosine kinases

Current Opinion in Biotechnology, 1995
The description in the past year of several novel protein tyrosine kinase inhibitors, which exhibit dramatic improvements in potency and specificity over earlier agents, will be considered a major turning point in the field. These compounds appear to have the necessary pharmacological properties to finally allow clarification of whether suppression of ...
David W. Fry, Alexander James Bridges
openaire   +3 more sources

Protein Tyrosine Kinase Activity Assays [PDF]

Current Protocols in Pharmacology, 1999
AbstractProtein tyrosine kinases (PTKs) are ubiquitous enzymes that are integrally involved in the regulation of transformation mechanisms, normal and pathological growth, cell cycle regulation, immune responses, and a variety of intracellular signaling mechanisms.
Brian E. Hawes, Tim van Biesen
openaire   +2 more sources

GPI-anchored cell-surface molecules complexed to protein tyrosine kinases.

Science, 1991
Binding of ligand or antibody to certain cell-surface proteins that are anchored to the membrane by glycophosphatidylinositol (GPI) can cause activation of leukocytes.
I. Štefanov́a, V. Hořejší, I. Ansotegui, W. Knapp, H. Stockinger   +4 more
semanticscholar   +1 more source