Results 291 to 300 of about 938,417 (319)

Protein Tyrosine Kinases in Human Brain and Gliomas

Journal of Neurochemistry, 1992
Abstract: Tyrosine kinase activity was determined in neonatal and adult human brain, oligodendrogliomas, and astrocytomas. The astrocytomas were divided into low‐ (grade I and grade II) and high‐grade (grade III and grade IV) tumors. We measured the tyrosine kinase activity in the cytosolic and membrane fraction using poly(glutamic acid:tyrosine, 4:1)
Jessica H. W. Heijden, Helmy E. van Erp, Gerard E.J. Staal, Cees W. M. van Veelen, Benedikte N. B. Maarschalkerweerd, Gert Rijksen   +5 more
openaire   +3 more sources

[29] Inhibition of protein-tyrosine kinases by tyrphostins

1991
Publisher Summary This chapter discusses the inhibition of protein-tyrosine kinases by tyrphostins. Many protein tyrosine kinases (PTKs) catalyze the phosphorylation of tyrosine residues on exogenous substrates and the autophosphorylation of tyrosine residues.
Aviv Gazit, Alexander Levitzki, Nir Osherov, Israel Posner, Chaim Gilon   +4 more
openaire   +3 more sources

The ErbB/HER family of protein-tyrosine kinases and cancer.

Pharmacological Research, 2014
R. Roskoski
semanticscholar   +1 more source

Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells

Critical reviews in clinical laboratory sciences, 2014
Elżbieta Gocek, A. Moulas, G. P. Studzinski   +2 more
semanticscholar   +1 more source

Receptor protein-tyrosine kinases and their signal transduction pathways.

Annual Review of Cell Biology, 1994
P. Geer, T. Hunter, R. Lindberg
semanticscholar   +1 more source

PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Science, 1997
Jing Li, Clifford Yen, D. Liaw, K. Podsypanina, S. Bose, Steven I. Wang, J. Puc, C. Miliaresis, L. Rodgers, R. Mccombie, S. Bigner, B. Giovanella, M. Ittmann, B. Tycko, H. Hibshoosh, M. Wigler, R. Parsons   +16 more
semanticscholar   +1 more source

The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases

Nature, 1993
D. Vetrie, I. Vořechovský, P. Sideras, P. Sideras, J. Holland, A. Davies, F. Flinter, L. Hammarström, C. Kinnon, R. Levinsky, M. Bobrow, C. I. E. Smith, D. Bentley   +12 more
semanticscholar   +1 more source

Beyond PI3Ks: targeting phosphoinositide kinases in disease

Nature Reviews Drug Discovery, 2023
Joanna Triscott, John E Burke, Brooke M Emerling   +2 more
exaly  

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

Nature, 1995
Songyang Zhou, K. Carraway, M. Eck, S. Harrison, R. Feldman, M. Mohammadi, J. Schlessinger, S. Hubbard, Darrin P. Smith, C. Eng, M. J. Lorenzo, B. Ponder, B. Mayer, L. Cantley   +13 more
semanticscholar   +1 more source

Cbl: many adaptations to regulate protein tyrosine kinases

Nature reviews. Molecular cell biology, 2001
C. Thien, W. Langdon
semanticscholar   +1 more source