Results 311 to 320 of about 333,854 (331)
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Tec protein‐tyrosine kinase is an effector molecule of Lyn proteni‐tyroenie kinase
The FASEB Journal, 1996The Tec family is a recently emerging subfamily among nonreceptor type protein‐tyrosine kinases (PTKs) consisting of Tec, Txk, Btk, Bmx, and Itk/Tsk/Emt. They have a long amino‐terminal unique region containing a pleckstrin homology domain and a Tec‐homology domain.
H, Mano +4 more
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src-related protein tyrosine kinases
1989Tyrosine protein kinases (TPKs) catalyze the transfer of phosphate groups from nucleotide triphosphates to tyrosine residues on proteins and peptides. While phosphorylation of proteins on tyrosine residues is a well-known post-radiational event detected in different regulatory systems, only a small number of cellular proteins are known substrates for ...
A, Veillette, J B, Bolen
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Structure and function of the protein tyrosine kinases
Progress in Growth Factor Research, 1990The protein tyrosine kinases (PTKs) are a large and structurally diverse family of enzymes. The conserved catalytic domain held in common by each member of this family is a self-contained 250-300 amino acid unit bearing sixteen highly conserved linear sequence elements, several of which have been shown to be important to the catalytic activity of this ...
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Mechanisms of Transformation by Protein-Tyrosine Kinases
1988In multicellular organisms there must be stringent control over the processes of cellular proliferation and differentiation. Thus sophisticated networks of regulatory molecules have evolved to sense and transmit signals within and between normal cells.
J C, Bell +6 more
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Platelet Protein Tyrosine Kinases
1997The first protein tyrosine kinase (PTK) to be identified, detected by Hunter and Sefton in 1979, was the transforming protein of the Rous sarcoma virus (Hunter and Sefton 1980). This 60-kDa phosphoprotein is encoded by the viral src oncogene (v-src) and is denoted pp60 v-src .
P. Presek, E. A. Martinson
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Oncogenic protein tyrosine kinases
Cellular and Molecular Life Sciences, 2004K. Pulford +7 more
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Purification of protein (tyrosine) kinases
1993Abstract This chapter describes the general principles involved in the purification of protein (tyrosine) kinases (PTKs). The importance of PTKs, and reasons for purifying them are briefly described. The best sources for protein (tyrosine) kinase purification, and methods for their assay are discussed.
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