Results 121 to 130 of about 15,507,347 (338)
Cell Communication and Signaling, 2020 Fibroblast growth factors (FGFs) via their receptors (FGFRs) transduce signals from the extracellular space to the cell interior, modulating pivotal cellular processes such as cell proliferation, motility, metabolism and death. FGF superfamily includes a
Martyna Sochacka +7 more
doaj +1 more source
Association of B-cell Lymphoma Protein-2 and Caspase-3 Expression in Ovarian Cancer [PDF]
, 2013 Ovarian cancer remains a major problem of women's health in the world, including Indonesia, and is associated with high rates of incidence and mortality. There are many efforts in early diagnosis on ovarian cancer, but until now there have not been found
Budiana, I. N. (I)
core
Protein—protein binding supersites
PLOS Computational Biology, 2019 The lack of a deep understanding of how proteins interact remains an important roadblock in advancing efforts to identify binding partners and uncover the corresponding regulatory mechanisms of the functions they mediate. Understanding protein-protein interactions is also essential for designing specific chemical modifications to develop new reagents ...
Raji Viswanathan +4 more
openaire +5 more sources
Brucella NyxA and NyxB dimerization enhances effector function during infection
FEBS Letters, EarlyView.Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre +4 more
wiley +1 more source
Clustering Coefficients of Protein-Protein Interaction Networks
, 2007 The properties of certain networks are determined by hidden variables that are not explicitly measured. The conditional probability (propagator) that a vertex with a given value of the hidden variable is connected to k of other vertices determines all ...
B. Alberts +4 more
core +1 more source
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Journal of Pharmacology and Pharmacotherapeutics, 2012 Research Collaborators for structural Bioinformatics Protein Data Bank (RCBS PDB) began in 1970’s by group of the young crystallographers, including Edgar Meyer, Gerson Coheon and Helen M Berman.[1] The project was initiated in 1971 to list the ...
S. Parasuraman
semanticscholar +1 more source
Light chain mutations contribute to defining the fibril morphology in systemic AL amyloidosis
Nature CommunicationsSystemic AL amyloidosis is one of the most frequently diagnosed forms of systemic amyloidosis. It arises from mutational changes in immunoglobulin light chains.
Sara Karimi-Farsijani +11 more
doaj +1 more source
Global protein function prediction in protein-protein interaction networks
, 2003 The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of single proteins
Flammini, A. +3 more
core +2 more sources
Mitochondrial protein import [PDF]
, 1994 The transport of nuclear-encoded proteins from the cytosol into mitochondria is mediated by targeting (signal) sequences present on precursor forms.
Neupert, Walter, Schwarz, Elisabeth
core +1 more source