Results 201 to 210 of about 5,365,325 (266)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Strategies to optimize the nutritional profile of mammalian meat for infants and geriatric population. [PDF]

Food Sci Anim Resour
Yoo MJY.
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Linear-time prediction of proteome-scale microbial protein interactions. [PDF]

Proc Natl Acad Sci U S A
Cornman A, Tranzillo M, Zulaybar NG, Bouzit I, Hwang Y.   +4 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

<i>Galleria mellonella</i> proteomic response to infection with <i>Streptococcus pyogenes</i>. [PDF]

Virulence
Abt-Becker C, Burzlaff J, Mikkat S, Kreikemeyer B, Patenge N.   +4 more
europepmc   +1 more source

Fasciola Metacercaria Contamination in Wetland Pastures and Its Association With Forage Characteristics Across Agro-Ecological Zones: Case of Gamo Zone, Southern Ethiopia. [PDF]

Vet Med Sci
Milkyas M, Kechero Y, Kaba T, Tora E, Endashaw G, Yehoannes T, Eligo N.   +6 more
europepmc   +1 more source

The moderating role of central adiposity, sex and age, on the association between animal- and plant-based protein intake and the 20-year cumulative incidence of type 2 diabetes: the ATTICA cohort study (2002-2022). [PDF]

Eur J Nutr
Kechagia I, Barkas F, Yannakoulia M, Liberopoulos E, Sfikakis PP, Pitsavos C, Panagiotakos D.   +6 more
europepmc   +1 more source

Repurposing the liquid-based Pap test for the detection of ovarian cancer protein biomarkers. [PDF]

Clin Proteomics
Skubitz APN, Boylan KLM, Liu L, Petersen A, Gao Y, Hansen JR, Trejo JB, Fillmore TL, Wang Y, Geller MA, Argenta PA, Hoffman S, Rodland K, Liu T, Piehowski PD.   +14 more
europepmc   +1 more source

Sheath-Liquid CE-MS Interface: A Robust Infusion Platform for Native IMS-MS Analysis of Protein Assemblies and Their Conformers. [PDF]

J Mass Spectrom
Pathak K, Brinkman D, Gomes FP.
europepmc   +1 more source