Results 211 to 220 of about 7,411,435 (267)

Protein–protein interactions

Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P.   +1 more
openaire   +3 more sources

Analysis of Protein-Protein Interactions by Protein Microarrays

2021
The analysis of the proteome and the interactome would be useful for a better understanding of the pathophysiology of several disorders, allowing the identification of potential specific markers for early diagnosis and prognosis, as well as potential targets of intervention.
Ana, Montero-Calle, Rodrigo, Barderas
openaire   +2 more sources

DISCOVERING PROTEIN–PROTEIN INTERACTIONS

Journal of Bioinformatics and Computational Biology, 2004
The ongoing genomics and proteomics efforts have helped identify many new genes and proteins in living organisms. However, simply knowing the existence of genes and proteins does not tell us much about the biological processes in which they participate. Many major biological processes are controlled by protein interaction networks.
See-Kiong Ng, Soon-Heng Tan
openaire   +2 more sources

Protein–protein association kinetics and protein docking

Current Opinion in Structural Biology, 2002
Rigid body protein docking methods frequently yield false positive structures that have good surface complementarity, but are far from the native complex. The main reason for this is the uncertainty of the protein structures to be docked, including the positions of solvent-exposed sidechains. Substantial efforts have been devoted to finding near-native
Carlos J, Camacho, Sandor, Vajda
openaire   +2 more sources

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