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Beyond olfaction: New insights into human odorant binding proteins. [PDF]

open access: yesProtein Sci
Chen M   +5 more
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Protein–protein interactions

Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P.   +1 more
openaire   +3 more sources

DISCOVERING PROTEIN–PROTEIN INTERACTIONS

Journal of Bioinformatics and Computational Biology, 2004
The ongoing genomics and proteomics efforts have helped identify many new genes and proteins in living organisms. However, simply knowing the existence of genes and proteins does not tell us much about the biological processes in which they participate. Many major biological processes are controlled by protein interaction networks.
See-Kiong, Ng, Soon-Heng, Tan
openaire   +2 more sources

Analyzing Protein–Protein Interaction Networks

Journal of Proteome Research, 2012
The advent of the "omics" era in biology research has brought new challenges and requires the development of novel strategies to answer previously intractable questions. Molecular interaction networks provide a framework to visualize cellular processes, but their complexity often makes their interpretation an overwhelming task.
Koh GC   +4 more
openaire   +2 more sources

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