Results 41 to 50 of about 120,253,457 (190)

The Senokine Gas6 Promotes Aortic Valve Calcification Through CaMKII–DRP1–Mediated Terminal Scission of Mitochondrial‐Derived Vesicles

open access: yesAging Cell, Volume 25, Issue 11, November 2026.
In age‐associated calcific aortic valve disease (CAVD), human valve tissues and calcifying human valvular interstitial cells (hVICs) exhibit senescence‐associated features, while calcifying hVICs hypersecrete mitochondrial‐derived vesicles (MDVs). Donut‐shaped mitochondria serve as physical platforms for MDV budding, whereas Gas6 promotes Ca2+–CaMKII ...
Yaoyu Zhang   +17 more
wiley   +1 more source

Anticipation of highly sensitised renal patients' immunoadsorption requirements by prescreening using protein A minicolumns

open access: yes, 1996
We are able to subdivide highly sensitised renal patients who wish to enter our immunoadsorption programme into two groups; those who will require acute pretransplant immunoadsorption only and those requiring regular immunoadsorption prior to ...
Higgins, R M   +7 more
core   +1 more source

Exploring the nursing characteristics and management for patients with high levels of human leukocyte antigen (HLA) - antibodies undergoing different desensitization strategies before allogeneic hematopoietic stem cell transplantation (allo-HSCT)

open access: yesZhongguo shuxue zazhi
[Objective] To investigate the efficacy, nursing characteristics, and management of different desensitization strategies before allogeneic hematopoietic stem cell transplantation (allo-HSCT) among patients with high level of human leukocyte antigen (HLA)
ZHOU Danping   +6 more
doaj   +1 more source

Effectiveness of LDL Apheresis Techniques for Reducing LDL‐C in Familial Hypercholesterolemia: A Systematic Review and Meta‐Analysis

open access: yesHealth Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Objective Familial hypercholesterolemia (FH) is a common inherited disorder characterized by markedly elevated low‐density lipoprotein cholesterol (LDL‐C) levels and an increased risk of premature cardiovascular disease. LDL apheresis is an extracorporeal procedure used to remove atherogenic lipoproteins from the circulation and is an ...
Naser Derakhshani   +7 more
wiley   +1 more source

Economic analysis of immunoadsorption systems

open access: yes, 2001
Immunoadsorption possesses an attractive combination of selectivity and yield, and in some cases may replace many conventional purification steps with a single step.
Ben Hunt   +9 more
core   +1 more source

Table_1_Treatment of Severe Japanese Encephalitis Complicated With Hashimoto’s Thyroiditis and Guillain-Barré Syndrome With Protein A Immunoadsorption: A Case Report.docx

open access: yes, 2022
A severely comatose female patient was diagnosed with Japanese encephalitis (JE). Her condition was complicated by Hashimoto’s thyroiditis (HT) and Guillain-Barré syndrome (GBS).
Liyang Long (11917637)   +10 more
core   +1 more source

Agonistic Autoantibodies to the β2-Adrenergic Receptor Involved in the Pathogenesis of Open-Angle Glaucoma

open access: yesFrontiers in Immunology, 2018
Glaucoma is a frequent ocular disease that may lead to blindness. Primary open-angle glaucoma (POAG) and ocular hypertension (OHT) are common diseases with increased intraocular pressure (IOP), which are mainly responsible for these disorders.
Anselm Jünemann   +15 more
doaj   +1 more source

A Novel Sequential Regimen of Efgartigimod and Telitacicept as Fast‐Acting Treatment for Impeding Crisis of MuSK‐MG

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular junction. The muscle‐specific kinase (MuSK) antibody‐positive subtype often involves bulbar and respiratory muscles, conferring a high risk of myasthenic crisis. Method We report a very late‐onset MuSK‐MG case complicated by lung infection and acute heart failure,
Tianjiao Duan   +3 more
wiley   +1 more source

Table_2_Treatment of Severe Japanese Encephalitis Complicated With Hashimoto’s Thyroiditis and Guillain-Barré Syndrome With Protein A Immunoadsorption: A Case Report.docx

open access: yes, 2022
A severely comatose female patient was diagnosed with Japanese encephalitis (JE). Her condition was complicated by Hashimoto’s thyroiditis (HT) and Guillain-Barré syndrome (GBS).
Liyang Long (11917637)   +10 more
core   +1 more source

Identification of a Lactylation‐Related Gene Signature and Candidate Biomarkers for Dilated Cardiomyopathy

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 18, September 2026.
ABSTRACT Dilated cardiomyopathy (DCM) is a leading cause of heart failure. Due to its complex pathogenesis, effective treatment strategies remain limited. Therefore, it is particularly important to identify novel candidate biomarkers from the pathogenesis level. In recent years, lactylation modification plays an important role in various cardiovascular
Xiaoyan Zhi   +6 more
wiley   +1 more source

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