Results 31 to 40 of about 120,253,457 (190)

“Multisystem Inflammatory Syndrome in Children”-Like Disease after COVID-19 Vaccination (MIS-V) with Potential Significance of Functional Active Autoantibodies Targeting G-Protein-Coupled Receptors (GPCR-fAAb) for Pathophysiology and Therapy

Children, 2023
Background: An infection with SARS-CoV-2 can trigger a systemic disorder by pathological autoimmune processes. A certain type of this dysregulation is known as Multisystemic inflammatory syndrome in children (MIS-C).
Marius Schmidt, Steven Hébert, Gerd Wallukat, Rolf Ponader, Tobias Krickau, Matthias Galiano, Heiko Reutter, Joachim Woelfle, Abbas Agaimy, Christian Mardin, André Hoerning, Bettina Hohberger   +11 more
doaj   +1 more source

Effectiveness and safety of efgartigimod in patients with anti‐NMDAR or anti‐LGI1 encephalitis and its 18F‐DPA714 PET imaging evaluation: A multicenter, single‐arm, prospective, observational real‐world study

Neuroprotection, EarlyView.
Abstract Background Efgartigimod disrupts the recycling of pathogenic IgG autoantibodies and may represent a candidate therapy for autoimmune encephalitis. This real‐world study evaluated the clinical efficacy, safety, and impact of efgartigimod on brain inflammation.
Huanyu Meng, Siqi Tu, Yifan Zhou, Ruinan Shen, Xiaoyu Chen, Zhaozhao Cheng, Limei Wang, Yan Wu, Jie Lu, Shengjun Wang, Yan Xu, Wanhui Lin, Sheng Chen   +12 more
wiley   +1 more source

IgE-immunoadsorption for severe allergy to multiple foods: A case series of five children

World Allergy Organization Journal, 2023
Background: Children with severe food allergy may present high risk of fatal anaphylaxis and a highly impaired quality of life. Anti IgE-treatment has been shown to be a promising approach as monotherapy for severe allergy to multiple foods.
Stefania Arasi, MD, PhD, MSC, Anna Lucia Piscitelli, MD, Arianna Cafarotti, MD, Beatrice Marziani, MD, Valentina Pecora, MD, Lamia Dahdah, MD, Giovanna Leone, MD, Giorgia Bracaglia, PhD, Ottavia Porzio, MD, Andrea Onetti Muda, MD, Alessandro Fiocchi, MD   +10 more
doaj   +1 more source

Allergen‐Functionalized Microfluidic Immunoadsorption Platform for Selective Depletion of Peanut‐Specific Antibodies From Whole Blood

Journal of Polymer Science, EarlyView.
We present a microfluidic immunoadsorption platform functionalized with a layer‐by‐layer (LbL) nanofilm composed of poly(diallyldimethylammonium chloride) (PDDA) and protein extract (PE) for selective capture of peanut‐specific antibodies directly from the whole blood obtained from a peanut allergy mouse model.
Hesaneh Ahmadi, Nur Hendri Wahyu Firdaus, Rutwik Joshi, Akhilesh Kumar Shakya, Wei Li   +4 more
wiley   +1 more source

Evaluation of an ABO antibody immunoadsorption column for reduction of anti‐A and anti‐B isoagglutinin titers in group O platelet units

Transfusion, EarlyView.
Abstract Background Clinical guidelines recommend transfusing ABO‐identical platelets where possible. However, the short shelf life of platelets (5–7 days) and stock availability mean ABO‐nonidentical platelet transfusions are sometimes unavoidable. Minor ABO‐incompatible platelet transfusions carry a risk of hemolysis due to donor anti‐A/B antibodies,
Melanie J. Robbins, Susan Proffitt, Gillian Eastwood, Sian Huish, Kurt Nilsson, Rebecca Cardigan   +5 more
wiley   +1 more source

Immunoadsorption inferior to plasma exchange in a patient with chronic inflammatory demyelinating polyradiculoneuropathy

, 2002
Staphylococcal protein A immunoadsorption and plasma exchange were compared for treating chronic inflammatory demyelinating polyrodiculoneuropathy.
Lunn, M P T, Hadden, R D M, Hughes, R A C, Bensa, S   +3 more
core   +1 more source

Anti-aquaporin-1 autoantibodies in patients with neuromyelitis optica spectrum disorders. [PDF]

PLoS ONE, 2013
Autoantibodies against aquaporin-4 (AQP4), a water channel in CNS astrocytes, are detected in ∼50-80% of patients with neuromyelitis optica spectrum disorders (NMOsd), characterized by longitudinally extensive transverse myelitis (LETM) and/or optic ...
John S Tzartos, Christos Stergiou, Konstantinos Kilidireas, Paraskevi Zisimopoulou, Thomas Thomaidis, Socrates J Tzartos   +5 more
doaj   +1 more source

Liquid Biopsy: Past, Present, and Future

MedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu, Dianjie Zeng, Keran Zhao, Yuxi Wang, Huijie Hu, Fei Deng, Yinhuai Wang, Liya Sun, Liangmin Fu   +8 more
wiley   +1 more source

Immunoadsorption Techniques and Its Current Role in the Intensive Care Unit [PDF]

, 2019
Immunoadsorption is an extracorporeal technique used for the removal of antibodies and molecules from the blood. A large number of different adsorbents are now available allowing for the non-selective removal of all subclasses of immunoglobulins such as ...
Patrick Hamilton, Rhodri Harris, Hamilton, Patrick, Harris, Rhodri, Mitra, Sandip, Sandip Mitra   +5 more
core   +1 more source

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension. [PDF]

PLoS ONE, 2008
Agonistic autoantibodies directed at the alpha(1)-adrenergic receptor (alpha(1)-AAB) have been described in patients with hypertension. We implied earlier that alpha(1)-AAB might have a mechanistic role and could represent a therapeutic target.To pursue ...
Katrin Wenzel, Hannelore Haase, Gerd Wallukat, Wolfgang Derer, Sabine Bartel, Volker Homuth, Florian Herse, Norbert Hubner, Herbert Schulz, Marion Janczikowski, Carsten Lindschau, Christoph Schroeder, Stefan Verlohren, Ingo Morano, Dominik N Muller, Friedrich C Luft, Rainer Dietz, Ralf Dechend, Peter Karczewski   +18 more
doaj   +1 more source