Results 151 to 160 of about 25,768,908 (251)

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

Advanced Materials Interfaces, EarlyView.
Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi, Aniruddh Murali, Ellen Juel Pørtner, Adam Cohen Simonsen, Francesca Serra   +4 more
wiley   +1 more source

Analytical validation of a multiplexed peptide microarray for multi-antigen Epstein-Barr virus serological profiling across diverse clinical specimens. [PDF]

Front Immunol
Peterson M, Hunter JGL, Gatalica Z, Rose I, Stafford P, Diehnelt CW.   +5 more
europepmc   +1 more source

Metal Compound‐Based Non‐Enzymatic Electrochemical Cholesterol Sensors: Emerging Materials and Mechanistic Insights

Advanced Materials Interfaces, EarlyView.
This review discusses recent progress in metal complex‐based, non‐enzymatic electrochemical sensors for cholesterol detection. We examine metal oxides, metal sulfides, and hybrid nanomaterials, highlighting their catalytic mechanisms and material design strategies.
Longfei (Jack) Yin, Chao‐Tsen (Rora) Chen, Jacopo Giaretta, Thanh‐Qua Nguyen, Hoang‐Phuong Phan, Fariba Dehghani, Syamak Farajikhah   +6 more
wiley   +1 more source

Conformational diversity in poly-HAMP arrays and its implications for signal transduction. [PDF]

Protein Sci
Coles M, Ewers CP, Albrecht R, Martinez-Goikoetxea M, Orlowska M, Martin J, Lupas AN, Hartmann MD, Dunin-Horkawicz S.   +8 more
europepmc   +1 more source

Antibody‐Precomplexed Hemagglutinin Constructs Multivalently Bind Sialylated Glycan Receptors with Variable Valencies

Advanced Materials Interfaces, EarlyView.
Hemagglutinin precomplexation with antibodies (Abs) results in broad valency distributions, though it increases the total avidity from mM to nM to high nM. The valency distribution and the orientation of multivalent HA‐Ab complexes determine the extent of binding to different types of assays, whether the receptors are displayed in 2D or 3D.
Daniel Y. E. L. Tambuwun, María Ríos Carrasco, Elif Uslu, Geert‐Jan P. H. Boons, Nadia J. Mokiem, Albert J. R. Heck, Victor C. Yin, Robert P. de Vries, Jurriaan Huskens   +8 more
wiley   +1 more source

Proteome-wide characterization of Plasmodium vivax antigens using a high-density peptide array. [PDF]

PLoS Pathog
Asawa R, Hazzard B, Ko K, Tebben K, Tan J, Cantaert T, Berry A, Tolia N, Popovici J, Serre D.   +9 more
europepmc   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source

Advances in protein microarray-based proteomics for gastric cancer applications in biomarker discovery, molecular subtyping, and precision oncology. [PDF]

Front Oncol
Wang P, Xiao YL, Luo S, Dong H, Huang RP.   +4 more
europepmc   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source

Extracellular Vesicle Surface Protein Profiling in Metabolic Dysfunction-associated Steatotic Liver Disease in Obesity. [PDF]

J Extracell Biol
Garcia NA, Kløve-Mogensen K, Cliff KL, Bæk R, Ulanowska M, Quezada JAD, Jørgensen MM, Handberg A, Mellergaard M.   +8 more
europepmc   +1 more source