Results 111 to 120 of about 4,013,382 (355)

Investigations in Serum Copper. I. Nature of Serum Copper and its Relation to the Iron-Binding Protein in Human Serum. [PDF]

, 1947
Carl Holmberg, C.‐B. Laurell, Åke Åkeson, Annikki Linnasalmi, Pentti Laukkanen   +4 more
openalex   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

STUDIES ON THE METABOLISM OF PLASMA PROTEINS IN THE NEPHROTIC SYNDROME. I. ALBUMIN, γ-GLOBULIN AND IRON-BINDING GLOBULIN 1 [PDF]

, 1956
David Gitlin, Charles A. Janeway, Lee E. Farr   +2 more
openalex   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

BINDING OF CORTICOSTEROIDS BY PLASMA PROTEINS. III. THE BINDING OF CORTICOSTEROID AND RELATED HORMONES BY HUMAN PLASMA AND PLASMA PROTEIN FRACTIONS AS MEASURED BY EQUILIBRIUM DIALYSIS12 [PDF]

, 1958
William H. Daughaday
openalex   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Development and Validation of an Improved HPLC-MS/MS Method for Quantifying Total and Unbound Lenalidomide in Human Plasma

Pharmaceutics
Background/Objectives: This study aimed to develop a fully validated HPLC-MS/MS method for quantifying total and unbound lenalidomide concentrations in human plasma.
Suhyun Lee, Seungwon Yang, Wang-Seob Shim, Eunseo Song, Seunghoon Han, Sung-Soo Park, Suein Choi, Sung Hwan Joo, Seok Jun Park, Beomjin Shin, Donghyun Kim, Hyeonsu Kim, Yujung Jung, Kyung-Tae Lee, Eun Kyoung Chung   +14 more
doaj   +1 more source

The Relation of Protein Binding to the Pharmacology and Antibacterial Activity of Penicillins X, G, Dihydro F, and K [PDF]

, 1947
Ralph Tompsett, SELMA M. SHULTZ, Walsh McDermott   +2 more
openalex   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Predicting Protein Binding of Drugs Using Abraham Parameters: Effect of Ionization

Journal of Mazandaran University of Medical Sciences, 2019
Background and purpose: Protein binding (PB) is an important pharmacokinetic parameter in drug discovery and development. In past years Abraham parameters were used to predict some physicochemical and pharmacokinetic properties of drugs.
Shadi Shayanfar, Ali Shayanfar
doaj