Results 191 to 200 of about 4,013,382 (355)
The nature of the enzymically catalysed binding of glucose to the protein coat of Colpoda steinii cysts [PDF]
B.J. Marshall, J. Tibbs
openalex +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The role of LRRC15-SCG5 in ECM protein binding as a prognostic signature for urothelial carcinoma. [PDF]
Dong SW+5 more
europepmc +1 more source
The binding of sodium dodecyl sulphate to various proteins [PDF]
Rosalind Pitt‐Rivers+1 more
openalex +1 more source
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Global analysis of excitotoxicity-induced alterations in RNA structure and RNA-protein binding in neurons. [PDF]
Alvarez-Periel E+7 more
europepmc +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias+12 more
wiley +1 more source
Identification of potential human targets for epigallocatechin gallate through a novel protein binding site screening approach. [PDF]
Hirci J+4 more
europepmc +1 more source