Results 251 to 260 of about 4,419,405 (356)

BioDolphin as a comprehensive database of lipid-protein binding interactions. [PDF]

Commun Chem
Yang LY, Ping K, Luo Y, McShan AC.
europepmc   +1 more source

Characterization of Insulin-Like Growth Factor II(IGF-II) and IGF Binding Proteins in Patients with Non-Islet-Cell Tumor Hypoglycemia.

, 1993
Izumi Fukuda, Naomi Hizuka, Kazue Takano, Kumiko Asakawa‐Yasumoto, KAZUO SHIZUME, Hiroshi Demura   +5 more
openalex   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

LABind: identifying protein binding ligand-aware sites via learning interactions between ligand and protein. [PDF]

Nat Commun
Zhang Z, Quan L, Wang J, Peng L, Chen Q, Zhang B, Cao L, Jiang Y, Li G, Nie L, Wu T, Lyu Q.   +11 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Automatic Explanation of Protein-Protein Binding Mechanism: A Preliminary Study. [PDF]

Comput Struct Bioinform (2024)
Tam JZ, Liu Y, Jain DS, Armstrong G, Chen BY.   +4 more
europepmc   +1 more source

Expression of a Secreted Fibroblast Growth Factor Binding Protein-1 (FGFBP1) in Angioproliferative Kaposi Sarcoma

, 2014
Patricio E. Ray
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Mapping the space of protein binding sites with sequence-based protein language models. [PDF]

Bioinformatics
Oruç T, Kadukova M, Davies TG, Verdonk M, Poelking C.   +4 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source