Results 1 to 10 of about 738,821 (242)

Aldolase A Accelerates Cancer Progression by Modulating mRNA Translation and Protein Biosynthesis via Noncanonical Mechanisms. [PDF]

Adv Sci (Weinh), 2023
Aldolase A (ALDOA), a crucial glycolytic enzyme, is often aberrantly expressed in various types of cancer. Although ALDOA has been reported to play additional roles beyond its conventional enzymatic role, its nonmetabolic function and underlying ...
Song J, Li H, Liu Y, Li X, Shi Q, Lei QY, Hu W, Huang S, Chen Z, He X.   +9 more
europepmc   +2 more sources

Protein biosynthesis at the ER: finding the right accessories. [PDF]

Mol Biol Cell, 2023
Shao S.
europepmc   +1 more source

Breast cancer prevention with liquiritigenin from licorice through the inhibition of aromatase and protein biosynthesis in high-risk women's breast tissue. [PDF]

Sci Rep, 2023
Hajirahimkhan A, Howell C, Bartom ET, Dong H, Lantvit DD, Xuei X, Chen SN, Pauli GF, Bolton JL, Clare SE, Khan SA, Dietz BM.   +11 more
europepmc   +1 more source

Design principles and functional basis of enantioselectivity of alanyl-tRNA synthetase and a chiral proofreader during protein biosynthesis. [PDF]

Nucleic Acids Res, 2023
Sivakumar K, Venkadasamy VL, Amudhan G, Ann KJ, Goud GK, Nayani K, Gogoi J, Kuncha SK, Mainkar PS, Kruparani SP, Sankaranarayanan R.   +10 more
europepmc   +1 more source

Quassinoid analogs exert potent antitumor activity via reversible protein biosynthesis inhibition in human colorectal cancer. [PDF]

Biochem Pharmacol, 2023
Wei N, Burnett J, Crocker DL, Huang Y, Li S, Wipf P, Chu E, Schmitz JC.   +7 more
europepmc   +1 more source

SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis. [PDF]

Cancer Res, 2022
Loevenich LP, Tschurtschenthaler M, Rokavec M, Silva MG, Jesinghaus M, Kirchner T, Klauschen F, Saur D, Neumann J, Hermeking H, Jung P.   +10 more
europepmc   +1 more source

Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis. [PDF]

Front Physiol, 2022
Caulier A, Jankovsky N, Gautier EF, El Nemer W, Guitton C, Ouled-Haddou H, Guillonneau F, Mayeux P, Salnot V, Bruce J, Picard V, Garçon L.   +11 more
europepmc   +1 more source

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis. [PDF]

Biomedicines, 2022
Nguyen HA, Vu SH, Jung S, Lee BS, Nguyen TNQ, Lee H, Lee HG, Myagmarjav D, Jo T, Choi Y, Lee MS.   +10 more
europepmc   +1 more source

A Lipoate-Protein Ligase Is Required for De Novo Lipoyl-Protein Biosynthesis in the Hyperthermophilic Archaeon Thermococcus kodakarensis. [PDF]

Appl Environ Microbiol, 2022
Jin JQ, Sato T, Hachisuka SI, Atomi H.
europepmc   +1 more source

Structural Studies Reveal the Role of Helix 68 in the Elongation Step of Protein Biosynthesis. [PDF]

mBio, 2022
Cimicata G, Fridkin G, Bose T, Eyal Z, Halfon Y, Breiner-Goldstein E, Fox T, Zimmerman E, Bashan A, de Val N, Wlodawer A, Yonath A.   +11 more
europepmc   +1 more source