Protein biosynthesis in mitochondria. [PDF]
Biochemistry (Mosc), 2013 Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great ...
Kuzmenko AV +6 more
europepmc +5 more sources
Prediction of Metabolic Pathways Involvement in Prokaryotic UniProtKB Data by Association Rule Mining [PDF]
, 2016 The widening gap between known proteins and their functions has encouraged the development of methods to automatically infer annotations. Automatic functional annotation of proteins is expected to meet the conflicting requirements of maximizing ...
Boudellioua, Imane +4 more
core +22 more sources
Current knowledge and recent advances in understanding metabolism of the model cyanobacterium Synechocystis sp. PCC 6803 [PDF]
, 2020 Cyanobacteria are key organisms in the global ecosystem, useful models for studying metabolic and physiological processes conserved in photosynthetic organisms, and potential renewable platforms for production of chemicals.
Lea-Smith, David +2 more
core +3 more sources
Emerging connections between small RNAs and phytohormones [PDF]
, 2020 Small RNAs (sRNAs), mainly including miRNAs and siRNAs, are ubiquitous in eukaryotes. sRNAs mostly negatively regulate gene expression via (post-)transcriptional gene silencing through DNA methylation, mRNA cleavage, or translation inhibition.
Dubois, Marieke +3 more
core +2 more sources
Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. [PDF]
, 2019 Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse ...
Baskar, Reema +3 more
core +2 more sources
Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β. [PDF]
, 2016 Mutations in human CLC-1 chloride channel are associated with the skeletal muscle disorder myotonia congenita. The disease-causing mutant A531V manifests enhanced proteasomal degradation of CLC-1.
Chen, Shu-Ching +7 more
core +1 more source
Metabolic modeling and analysis of the metabolic switch in Streptomyces coelicolor [PDF]
, 2010 Background The transition from exponential to stationary phase in Streptomyces coelicolor is accompanied by a major metabolic switch and results in a strong activation of secondary metabolism.
Alam, Mohammad T. +6 more
core +10 more sources
β-n-oxalyl-l-α, β -diaminopropionic acid (β -odap) content in lathyrus sativus: The integration of nitrogen and sulfur metabolism through β -cyanoalanine synthase [PDF]
, 2017 Grass pea (Lathyrus sativus L.) is an important legume crop grown mainly in South Asia and Sub-Saharan Africa. This underutilized legume can withstand harsh environmental conditions including drought and flooding.
Chen, Peng +4 more
core +3 more sources
It takes two to tango: NAD+ and sirtuins in aging/longevity control [PDF]
, 2016 The coupling of nicotinamide adenine dinucleotide (NAD+) breakdown and protein deacylation is a unique feature of the family of proteins called ‘sirtuins.’ This intimate connection between NAD+ and sirtuins has an ancient origin and provides a ...
Guarente, Leonard, Imai, Shin-ichiro
core +2 more sources
The ubiK protein is an accessory factor necessary for bacterial Ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ [PDF]
, 2017 Ubiquinone (UQ), also referred to as coenzyme Q, is a widespread lipophilic molecule in both prokaryotes and eukaryotes in which it primarily acts as an electron carrier.
Aussel, Laurent +7 more
core +1 more source