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Aldolase A Accelerates Cancer Progression by Modulating mRNA Translation and Protein Biosynthesis via Noncanonical Mechanisms [PDF]
Advanced Science, 2023 Aldolase A (ALDOA), a crucial glycolytic enzyme, is often aberrantly expressed in various types of cancer. Although ALDOA has been reported to play additional roles beyond its conventional enzymatic role, its nonmetabolic function and underlying ...
Junjiao Song +9 more
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Protein biosynthesis in mitochondria. [PDF]
Biochemistry (Mosc), 2013 Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great ...
Kuzmenko AV +6 more
europepmc +4 more sources
Deoxynivalenol Affects Cell Metabolism and Increases Protein Biosynthesis in Intestinal Porcine Epithelial Cells (IPEC-J2): DON Increases Protein Biosynthesis [PDF]
Toxins, 2018 Deoxynivalenol (DON) is a toxin found in cereals as well as in processed products such as pasta, and causes substantial economic losses for stock breeding as it induces vomiting, reduced feeding, and reduced growth rates in piglets.
Constanze Nossol +8 more
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Transimulation - protein biosynthesis web service. [PDF]
PLoS ONE, 2013 Although translation is the key step during gene expression, it remains poorly characterized at the level of individual genes. For this reason, we developed Transimulation - a web service measuring translational activity of genes in three model organisms:
Marlena Siwiak, Piotr Zielenkiewicz
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Pathway and protein engineering for biosynthesis
Synthetic and Systems Biotechnology, 2022 Sustainable biosynthesis of chemicals and efforts to create new molecules of interest require efficient enzymes and pathways as well as comprehensive tools and technologies to implement this rewiring. Enzymes are the key components for construction of efficient biosynthetic pathways, enzyme characterization and engineering can help to identify key ...
Yongjin Zhou +2 more
doaj +4 more sources
Mechanism of protein biosynthesis [PDF]
Bacteriological Reviews, 1969 Péter Lengyel, Dieter Söll
openalex +4 more sources
Ribosome Pool Engineering Increases Protein Biosynthesis Yields [PDF]
ACS Central ScienceCamila Kofman +3 more
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Frontiers in Pharmacology, 2021 Missense mutations in the gene that encodes for the mechanically-gated ion channel Piezo1 have been linked to a number of diseases. Gain-of-function variants are linked to a hereditary anaemia and loss-of-function variants have been linked to generalized
Zijing Zhou +5 more
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Current Issues in Molecular Biology, 2022 We hypothesized that the general control nonderepressible 2 (GCN2)/eukaryotic initiation factor 2 (eIF2) signaling pathway and intracellular protein synthesis (PS) are regulated to maintain milk PS in primary bovine mammary epithelial cells (MECs) under ...
Zulma Tatiana Ruiz-Cortés +2 more
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