Results 11 to 20 of about 751,544 (357)

Cryoprotective agents affect amino acids incorporation into total proteins in cells of lymphoid organs and liver of experimental animals [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2020
The effect of penetrating (glycerol, DMSO) and poorly penetrating (PEG-400) cryoprotective agents on labeled amino acids incorporation into de novo synthesized proteins in the cells of mice thymus, lymph nodes, spleen and cell-free rat liver extract was ...
A. K. Gulevskyy   +2 more
doaj   +1 more source

Supernatants of Bifidobacterium longum and Lactobacillus plantarum Strains Exhibited Antioxidative Effects on A7R5 Cells

open access: yesMicroorganisms, 2021
Vascular reactive oxygen species (ROS) play an essential role in cardiovascular diseases and the antioxidative effects of probiotics have been widely reported.
Yusheng Wang   +7 more
doaj   +1 more source

Natural Product Inhibition and Enzyme Kinetics Related to Phylogenetic Characterization for Bacterial Peptidyl-tRNA Hydrolase 1

open access: yesMolecules, 2021
With the relentless development of drug resistance and re-emergence of many pathogenic bacteria, the need for new antibiotics and new antibiotic targets is urgent and growing. Bacterial peptidyl-tRNA hydrolase, Pth1, is emerging as a promising new target
D. Scott Strange   +6 more
doaj   +1 more source

Recombinant HNP-1 Produced by Escherichia coli Triggers Bacterial Apoptosis and Exhibits Antibacterial Activity against Drug-Resistant Bacteria

open access: yesMicrobiology Spectrum, 2022
Human neutrophil peptide-1 (HNP-1) is a promising antibiotic candidate, but its clinical applications have been hampered by challenges during mass production and an inadequate understanding of its bactericidal mechanisms.
Qi Xie   +11 more
doaj   +1 more source

Emerging connections between small RNAs and phytohormones [PDF]

open access: yes, 2020
Small RNAs (sRNAs), mainly including miRNAs and siRNAs, are ubiquitous in eukaryotes. sRNAs mostly negatively regulate gene expression via (post-)transcriptional gene silencing through DNA methylation, mRNA cleavage, or translation inhibition.
Dubois, Marieke   +3 more
core   +2 more sources

Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. [PDF]

open access: yes, 2019
Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse ...
Baskar, Reema   +3 more
core   +2 more sources

Regulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β. [PDF]

open access: yes, 2016
Mutations in human CLC-1 chloride channel are associated with the skeletal muscle disorder myotonia congenita. The disease-causing mutant A531V manifests enhanced proteasomal degradation of CLC-1.
Chen, Shu-Ching   +7 more
core   +1 more source

Catholic Social Services, Inc. v. C.A.A.: Best Interests and Statutory Construction of the Indian Child Welfare Act [PDF]

open access: yes, 1990
The concept of "proteoglycans" as discrete molecules surfaced some 40 years ago, out of previously muddled notions of the extracellular matrix. Core proteins were gradually recognized as molecular entities, distinct with regard to location, substitution ...
Nazarian, Douglas R.
core   +2 more sources

New Chloramphenicol Derivatives from the Viewpoint of Anticancer and Antimicrobial Activity

open access: yesAntibiotics, 2019
Over the last years, we have been focused on chloramphenicol conjugates that combine in their structure chloramphenicol base with natural polyamines, spermine, spermidine and putrescine, and their modifications.
Panagiota C. Giannopoulou   +8 more
doaj   +1 more source

The Streptomyces coelicolor small ORF trpM stimulates growth and morphological development and exerts opposite effects on actinorhodin and calcium-dependent antibiotic production [PDF]

open access: yes, 2020
In actinomycetes, antibiotic production is often associated with a morpho-physiological differentiation program that is regulated by complex molecular and metabolic networks. Many aspects of these regulatory circuits have been already elucidated and many
Alberto Vassallo   +7 more
core   +2 more sources

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