Results 11 to 20 of about 492,163 (307)

Natural Product Inhibition and Enzyme Kinetics Related to Phylogenetic Characterization for Bacterial Peptidyl-tRNA Hydrolase 1

open access: yesMolecules, 2021
With the relentless development of drug resistance and re-emergence of many pathogenic bacteria, the need for new antibiotics and new antibiotic targets is urgent and growing. Bacterial peptidyl-tRNA hydrolase, Pth1, is emerging as a promising new target
D. Scott Strange   +6 more
doaj   +1 more source

Supernatants of Bifidobacterium longum and Lactobacillus plantarum Strains Exhibited Antioxidative Effects on A7R5 Cells

open access: yesMicroorganisms, 2021
Vascular reactive oxygen species (ROS) play an essential role in cardiovascular diseases and the antioxidative effects of probiotics have been widely reported.
Yusheng Wang   +7 more
doaj   +1 more source

Recombinant HNP-1 Produced by Escherichia coli Triggers Bacterial Apoptosis and Exhibits Antibacterial Activity against Drug-Resistant Bacteria

open access: yesMicrobiology Spectrum, 2022
Human neutrophil peptide-1 (HNP-1) is a promising antibiotic candidate, but its clinical applications have been hampered by challenges during mass production and an inadequate understanding of its bactericidal mechanisms.
Qi Xie   +11 more
doaj   +1 more source

New Chloramphenicol Derivatives from the Viewpoint of Anticancer and Antimicrobial Activity

open access: yesAntibiotics, 2019
Over the last years, we have been focused on chloramphenicol conjugates that combine in their structure chloramphenicol base with natural polyamines, spermine, spermidine and putrescine, and their modifications.
Panagiota C. Giannopoulou   +8 more
doaj   +1 more source

Transimulation - protein biosynthesis web service. [PDF]

open access: yesPLoS ONE, 2013
Although translation is the key step during gene expression, it remains poorly characterized at the level of individual genes. For this reason, we developed Transimulation - a web service measuring translational activity of genes in three model organisms:
Marlena Siwiak, Piotr Zielenkiewicz
doaj   +1 more source

Elucidation of transient protein-protein interactions within carrier protein-dependent biosynthesis

open access: yesCommunications Biology, 2021
Using structural and computational analysis, Bartholow et al. perform a comprehensive residue-by-residue comparison of the protein-protein interactions in de novo fatty acid biosynthesis that occurs in E. coli. This study provides insights into molecular
Thomas G. Bartholow   +6 more
doaj   +1 more source

Biosynthesis of Red Elemental Selenium Protein [PDF]

open access: yesE3S Web of Conferences, 2019
The red elemental selenoprotein was biosynthesized by active dry yeast in this study. Through a single factor experiment and L9(34)-orthogonal test fermentation condition optimization, the selenium content was 15.72 mg/g under optimal condition.
Wu Guojie   +4 more
doaj   +1 more source

Biosynthesis of microvillar proteins [PDF]

open access: yesBiochemical Journal, 1984
Udgivelsesdato: 1984-Jul ...
Danielsen, E M   +3 more
openaire   +3 more sources

Proteome analysis of sesame leaves in response to waterlogging stress at vegetative and flowering stages

open access: yesBiologia Plantarum, 2019
Waterlogging, a major environmental stress, impairs plant growth and development and induces synthesis of different proteins. To understand the molecular mechanisms coupled with morpho-physiological alterations underlying waterlogging tolerance, the LTQ ...
H.-J. JUNG   +6 more
doaj   +1 more source

Structural Analysis of an l-Cysteine Desulfurase from an Ssp DNA Phosphorothioation System

open access: yesmBio, 2020
DNA phosphorothioate (PT) modification, in which the nonbridging oxygen in the sugar-phosphate backbone is substituted by sulfur, is catalyzed by DndABCDE or SspABCD in a double-stranded or single-stranded manner, respectively.
Liqiong Liu   +14 more
doaj   +1 more source

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