Results 191 to 200 of about 6,168,631 (284)

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren   +11 more
wiley   +1 more source

Coordinated improvement of maize grain yield and protein quality by the ZmMADS8-ZmMADS47-O2 module and a G protein gamma subunit

open access: yesCrop Journal
Improving protein quality and grain yield traits coordinately is an important goal for crop breeding. To date, many protein-quality or grain-yield regulation genes have been identified.
Yunfu Li   +11 more
doaj  

Deciphering the Transcriptional Regulatory Network Governing Starch and Storage Protein Biosynthesis in Wheat for Breeding Improvement. [PDF]

open access: yesAdv Sci (Weinh)
Zhao L   +14 more
europepmc   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

open access: yesAdvanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao   +17 more
wiley   +1 more source

Pathway and protein engineering for biosynthesis

open access: yesSynthetic and Systems Biotechnology, 2022
Yongjin Zhou   +2 more
doaj  

Comprehensive translational profiling and STE AI uncover rapid control of protein biosynthesis during cell stress. [PDF]

open access: yesNucleic Acids Res
Horvath A   +9 more
europepmc   +1 more source

Mechanism of protein biosynthesis in mammalian mitochondria.

open access: yesBiochimica et Biophysica Acta, 2012
Brooke E. Christian, L. Spremulli
semanticscholar   +1 more source

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