Results 1 to 10 of about 1,141,379 (303)

Thrombosis-related characteristics of pregnant women with antithrombin deficiency, protein C deficiency and protein S deficiency in Japan [PDF]

Thrombosis Journal
Background  We previously conducted a primary survey of pregnant women with hereditary thrombophilia based on national surveillance in Japan, but did not examine their thrombosis-related characteristics.
Takao Kobayashi, Kazuko Sugiura, Toshiyuki Ojima, Mariko Serizawa, Kyuya Hirai, Eriko Morishita   +5 more
doaj   +2 more sources

Surgical treatment of traction retinal detachment associated with compound heterozygous congenital protein C deficiency [PDF]

American Journal of Ophthalmology Case Reports, 2023
Purpose: Congenital protein C deficiency leads to a prothrombotic state that may result in potentially sight- and life-threatening thromboembolic attacks.
Tomoki Kurihara, Takao Endo, Shumpei Obata, Taeko Hotta, Naoki Nishio, Takayuki Iwaibara, Katsuya Hirata, Sakina Kuge, Yuhei Konishi, Daisuke Yoshida, Takahide Yanagi, Takashi Taga, Kazuko Wada, Norihisa Wada, Shouichi Ohga, Shunji Kusaka   +15 more
doaj   +2 more sources

Comprehensive literature review of protein C concentrate use in patients with severe congenital protein C deficiency [PDF]

Research and Practice in Thrombosis and Haemostasis
Severe congenital protein C deficiency (SCPCD) is a rare disorder associated with life-threatening purpura fulminans and disseminated intravascular coagulation that typically present within hours after birth.
Csaba Siffel, Abhinav Wadhwa, Vanita Tongbram, Margaret Katana Ogongo, Henrik Sliwka, Hanna T. Gazda, Peter L. Turecek   +6 more
doaj   +2 more sources

Evaluation of pharmacokinetics of intravenous protein C concentrate in protein C deficiency: implications for treatment initiation and maintenance [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Dosing of intravenous protein C concentrate (Ceprotin) in patients with protein C deficiency is guided by pharmacokinetics (PK) of plasma protein C activity.
Zhaoyang Li, Inmaculada C. Sorribes, Jennifer Schneider, Adekemi Taylor   +3 more
doaj   +2 more sources

Congenital protein C deficiency and thrombosis in a dog [PDF]

Journal of Veterinary Internal Medicine, 2020
Congenital protein C deficiency is an important cause of thrombosis in humans but is not described in dogs. A 4‐year‐old Hungarian Vizsla was presented for investigation of acute onset of ascites.
Darren Kelly, Florence Juvet, Gary Moore
doaj   +2 more sources

Severe protein C deficiency in a newborn caused by a homozygous pathogenic variant in the PROC gene: a case report [PDF]

BMC Pediatrics, 2021
Background Severe protein C deficiency is a rare and inherited cause of thrombophilia in neonates. Protein C acts as an anticoagulant, and its deficiency results in vascular thrombosis.
Uisook Song, Young Hye Ryu, Kiteak Hong, So-Yeon Shim, Seongyeol Park, Jeong Seok Lee, Young Seok Ju, Seung Han Shin, Soyoung Lee   +8 more
doaj   +2 more sources

Pharmacokinetic Evidence Supporting Subcutaneous Use of Protein C Concentrate in Patients with Protein C Deficiency [PDF]

TH Open
Zhaoyang Li, Inmaculada C. Sorribes, Jennifer Schneider, Adekemi Taylor   +3 more
doaj   +2 more sources

A quantitative assay system for protein C activity, the regulator of blood coagulation, based on a chromogenic method mimicking the blood coagulation cascade

Practical Laboratory Medicine, 2023
Background and aims: Protein C is a plasma protein, and its active form regulates blood coagulation. The recommended unit of protein C activity is IU/mL; however, some laboratories use percentage. Some deficiencies cannot be detected owing to measurement
Ryo Matsuda, Ruri Someya, Mutsumi Kobayashi, Eri Nakao, Momoka Hamasaki, Misuzu Shigeta, Hinako Hatae, Hiroyuki Kuma   +7 more
doaj   +1 more source

Protein C Deficiency [PDF]

Archives of Pathology & Laboratory Medicine, 2019
Protein C (PC) deficiency is a heritable or acquired risk factor for thrombophilia, with presentations varying from asymptomatic to venous thromboembolism to neonatal purpura fulminans, a life-threatening disorder. Hereditary PC deficiency is caused by mutation in the PC (PROC) gene located on chromosome 2q14.3.
Peyman, Dinarvand, Karen A, Moser
openaire   +2 more sources

Protein C deficiency [PDF]

Indian Journal of Hematology and Blood Transfusion, 2013
This report describes a 4 year old female child who presented with fever, pain and swelling of left leg following a trivial trauma. She was diagnosed as a case of deep vein thrombosis and subsequently found to be due to protein C deficiency.
Arun K, De, Somnath, Pal, Santanu, Das, Tunisa, Bhattacharya   +3 more
openaire   +2 more sources