Results 51 to 60 of about 22,165,413 (298)
Southern African Journal of HIV Medicine, 2021 Background: HIV is a chronic inflammatory state with the production of many acute-phase-reactant proteins. Some of these proteins have procoagulant activities that predispose HIV-infected patients to thrombosis.
Fatai O. Bello +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
American Journal of Perinatology Reports, 2018 Severe protein C (PC) deficiency leads to purpura fulminans and stroke in newborns. However, the clinical impact of plasma PC activity on the development of neonatal cerebral disease remains elusive. We report a case of hemorrhagic stroke associated with
Erika Uehara +9 more
doaj +1 more source
A Study of Prothrombotic Factors in Human Immunodeficiency Virus-Infected Patients
Indian Journal of Medical Specialities, 2021 Introduction: Human immunodeficiency virus (HIV) infection has been described as a hypercoagulable state. Some studies suggest that thrombotic events may be 2–10 times more prevalent in this group than in the general population.
Meena Lanjiwar +3 more
doaj +1 more source
Acute Reversal of Warfarin Therapy in Patient with Protein C and S Deficiency Presenting for Emergency Surgery [PDF]
, 2010 This is a case report of a 19 year young male presented with swelling and blackening of right upper limb and abdominal pain since 10 days. He was a known case of protein C and protein S deficiency on warfarin therapy, with deranged coagulation parameters
Bharti D Kondwilkar +3 more
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Free-floating left atrial thrombi with acquired protein C deficiency in hepatitis
Romanian Journal of Cardiology, 2023 A 43-year-old woman with a recent history of confirmed hepatitis B presented with yellow sclera and dyspnea. Clinically, she had tachycardia and tachypnea as well as signs of jaundice and right upper quadrant pain.
Sabzi Feridoun +2 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Unveiling Procoagulant States in Acute Pulmonary Embolism: A Case Series and Insights [PDF]
Journal of Clinical and Diagnostic ResearchVenous Thromboembolism (VTE) is a common yet potentially life-threatening condition. The most frequent presentations of venous thrombosis are Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE).
Padamati Advytha Reddy +4 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source