Protein conformation stabilized by newly formed turns for thermal resilience. [PDF]
Tang R, Gasvoda KL, Rabin J, Alsberg E.
europepmc +1 more source
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva +5 more
wiley +1 more source
The role of G protein conformation in receptor-G protein selectivity. [PDF]
Jang W, Lu S, Xu X, Wu G, Lambert NA.
europepmc +1 more source
Changes in Ultraviolet Absorption Produced by Alteration of Protein Conformation
John W. Donovan
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Determination of protein conformation and orientation at buried solid/liquid interfaces. [PDF]
Guo W +5 more
europepmc +1 more source
On the Conformational Stability of Globular Proteins
Peter H. von Hippel, Kwok-Ying Wong
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Membrane proteins specified by herpes simplex viruses. IV. Conformation of the virion glycoprotein designated VP7(B2) [PDF]
M Sarmiento, Patricia G. Spear
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ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee +9 more
wiley +1 more source
Effect of cavitation jet technology on instant solubility characteristics of soymilk flour: Based on the change of protein conformation in soymilk. [PDF]
Gong Q +8 more
europepmc +1 more source

