FEBS Open Bio, EarlyView.This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
Probing DNA- and ATP-mediated Conformational Changes in the MutS Family of Mispair Recognition Proteins Using Deuterium Exchange Mass Spectrometry [PDF]
, 2010 Marc L. Mendillo +6 more
openalex +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Kinetic Rate Constant Prediction Supports the Conformational Selection Mechanism of Protein Binding
, 2012 Iain H. Moal, Paul A. Bates
openalex +2 more sources
A probabilistic view of protein stability, conformational specificity, and design [PDF]
, 2023 Jacob Stern +8 more
openalex +1 more source
Codon usage bias regulates gene expression and protein conformation in yeast expression system P. pastoris. [PDF]
Microb Cell Fact, 2021 Xu Y +6 more
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Protein Conformation Governs Spin-Selective Electron Transmission. [PDF]
J Phys Chem LettPreeyanka N, Das TK, Naaman R.
europepmc +1 more source
Association between Predicted Effects of TP53 Missense Variants on Protein Conformation and Their Phenotypic Presentation as Li-Fraumeni Syndrome or Hereditary Breast Cancer. [PDF]
Int J Mol Sci, 2021 Liu Y +7 more
europepmc +1 more source